The recognition of fungal cells by the host immune system is key during the establishment of
a protective anti-fungal response. Even though the immune system has evolved a vast …

Paracoccidioides spp. are dimorphic fungal pathogens responsible for one of the most
relevant systemic mycoses in Latin America, paracoccidioidomycosis (PCM). Their exact …

The Paracoccidioides genus includes two species of thermally dimorphic fungi that cause
paracoccidioidomycosis, a neglected health-threatening human systemic mycosis endemic …

Human fungal pathogens are a deadly and underappreciated risk to global health that most
severely affect immunocompromised individuals. A virulence attribute shared by some of the …

Iron is an essential nutrient for all organisms. For pathogenic fungi, iron is essential for the
success of infection. Thus, these organisms have developed high affinity iron uptake …

Fungi are among the most successful eukaryotes on Earth: they have evolved strategies to
survive in the most diverse environments and stressful conditions and have been selected …

Paracoccidioidomycosis (PCM) is the most relevant systemic endemic mycosis limited to
Latin American countries. The etiological agents are thermally dimorphic species of the …

Extracellular vesicles (EVs) are cellular components involved in cargo delivery to the
extracellular environment, including the fungal cell wall. Their importance in cell–cell …

The reliability of qRT-PCR results depend on the stability of reference genes used for
normalization, suggesting the necessity of identification of reference genes before gene …

Amphotericin B (AmB) has been widely used against fungal infections throughout almost the
entire body, including the skin, nails, oral cavity, respiratory tract, and urinary tract. However …