Estrogen receptor beta as target for colorectal cancer prevention
Colorectal cancer (CRC) is a leading cause of death in the United States. Despite its slow
development and the capacity for early diagnosis, current preventive approaches are not …
development and the capacity for early diagnosis, current preventive approaches are not …
Harnessing the genome for characterization of G‐protein coupled receptors in cancer pathogenesis
ME Feigin - The FEBS journal, 2013 - Wiley Online Library
G‐protein coupled receptors (GPCRs) mediate numerous physiological processes and
represent the targets for a vast array of therapeutics for diseases ranging from depression to …
represent the targets for a vast array of therapeutics for diseases ranging from depression to …
Exosome-like nanoparticles from intestinal mucosal cells carry prostaglandin E2 and suppress activation of liver NKT cells
ZB Deng, X Zhuang, S Ju, X Xiang, J Mu… - The Journal of …, 2013 - journals.aai.org
Regulation and induction of anergy in NKT cells of the liver can inhibit autoimmune and
antitumor responses by mechanisms that are poorly understood. We investigated the effects …
antitumor responses by mechanisms that are poorly understood. We investigated the effects …
Proline oxidase, a p53-induced gene, targets COX-2/PGE2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers
Y Liu, GL Borchert, A Surazynski, JM Phang - Oncogene, 2008 - nature.com
Proline oxidase (POX), a flavoenzyme localized at the inner mitochondrial membrane,
catalyzes the first step of proline degradation by converting proline to pyrroline-5 …
catalyzes the first step of proline degradation by converting proline to pyrroline-5 …
High blood sugar levels but not diabetes mellitus significantly enhance oxaliplatin chemoresistance in patients with stage III colorectal cancer receiving adjuvant …
IP Yang, ZF Miao, CW Huang, HL Tsai… - Therapeutic …, 2019 - journals.sagepub.com
Background: The high prevalence of type 2 diabetes mellitus (DM) among patients with
colorectal cancer (CRC) is becoming a serious public health concern worldwide. FOLFOX4 …
colorectal cancer (CRC) is becoming a serious public health concern worldwide. FOLFOX4 …
[HTML][HTML] High blood sugar levels significantly impact the prognosis of colorectal cancer patients through down-regulation of microRNA-16 by targeting Myb and …
IP Yang, HL Tsai, CW Huang, CY Lu, ZF Miao… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The high prevalence of type 2 diabetes mellitus in colorectal cancer patients is a crucial
public health issue worldwide. The deregulation of microRNAs has been shown to be …
public health issue worldwide. The deregulation of microRNAs has been shown to be …
Multifunctional microspherical magnetic and pH responsive carriers for combination anticancer therapy engineered by droplet-based microfluidics
pH stimuli responsive drug delivery platforms that can target specific locations along the
gastrointestinal tract hold great promise for colorectal cancer therapy. Herein, we present a …
gastrointestinal tract hold great promise for colorectal cancer therapy. Herein, we present a …
Identification of 5-fluorouracil response proteins in colorectal carcinoma cell line SW480 by two-dimensional electrophoresis and MALDI-TOF mass spectrometry
CSC Wong, VWK Wong, CML Chan… - Oncology …, 2008 - spandidos-publications.com
Colorectal cancer (CRC) is the second most prevalent cause of cancer-related deaths in the
Western world. 5-Fluorouracil (5-FU) is a standard chemotherapeutic drug to treat CRC …
Western world. 5-Fluorouracil (5-FU) is a standard chemotherapeutic drug to treat CRC …
Celecoxib and GABA cooperatively prevent the progression of pancreatic cancer in vitro and in xenograft models of stress-free and stress-exposed mice
HAN Al-Wadei, MH Al-Wadei, MF Ullah, HM Schuller - 2012 - journals.plos.org
Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis and is associated with
high levels of psychological distress. We have shown that beta-adrenergic receptors (β …
high levels of psychological distress. We have shown that beta-adrenergic receptors (β …
GIV/Girdin is a rheostat that fine-tunes growth factor signals during tumor progression
P Ghosh, M Garcia-Marcos… - Cell adhesion & …, 2011 - Taylor & Francis
GIV/Girdin is a multidomain signaling molecule that enhances PI3K-Akt signals downstream
of both G protein-coupled and growth factor receptors. We previously reported that GIV …
of both G protein-coupled and growth factor receptors. We previously reported that GIV …