To build health equity for an aging world marked by dramatic disparities in healthy lifespan
between countries, regions and population groups, research at the intersections of biology …

Physical activity has been demonstrated to have a significant impact on gut microbial
diversity and function. Emerging research has revealed certain aspects of the complex …

Patients with primary mitochondrial oxidative phosphorylation (OxPhos) defects present with
fatigue and multi-system disorders, are often lean, and die prematurely, but the mechanistic …

Exposure to any number of stressors during the first 1000 days from conception to age 2
years is important in shaping an individual's life trajectory of health and disease. Despite the …

Stress triggers anticipatory physiological responses that promote survival, a phenomenon
termed allostasis. However, the chronic activation of energy-dependent allostatic responses …

A clear, inclusive, and accurate approach to the collection of demographic information in
clinical research and medical practice is critical to understanding the healthcare needs of …

Although mitochondrial dysfunction is known to play an essential role in the pathophysiology
of bipolar disorder (BD), there is a glaring gap in our understanding of how mitochondrial …

Engaging in contemplative practice like meditation, yoga, and prayer, is beneficial for
psychological and physical well-being. Recent research has identified several underlying …

Adolescent individuals exhibit great variability in cortical dynamics and behavioral
outcomes. The developing adolescent brain is highly sensitive to social experiences and …

The prevailing notion that mitochondrial diseases arise from ATP deficiency is challenged by
recent evidence that oxidative phosphorylation defects trigger maladaptive stress responses …