[HTML][HTML] Oxidative stress in the light-exposed retina and its implication in age-related macular degeneration
Y Ozawa - Redox biology, 2020 - Elsevier
The retina continuously receives light to enable vision, and the related processes require a
marked amount of energy. During active metabolism, reactive oxygen species (ROS) are …
marked amount of energy. During active metabolism, reactive oxygen species (ROS) are …
Relationships between neurodegeneration and vascular damage in diabetic retinopathy
MG Rossino, M Dal Monte, G Casini - Frontiers in neuroscience, 2019 - frontiersin.org
Diabetic retinopathy (DR) is a common complication of diabetes and constitutes a major
cause of vision impairment and blindness in the world. DR has long been described …
cause of vision impairment and blindness in the world. DR has long been described …
Inherited retinal dystrophies: role of oxidative stress and inflammation in their physiopathology and therapeutic implications
I Pinilla, V Maneu, L Campello, L Fernández-Sánchez… - Antioxidants, 2022 - mdpi.com
Inherited retinal dystrophies (IRDs) are a large group of genetically and clinically
heterogeneous diseases characterized by the progressive degeneration of the retina …
heterogeneous diseases characterized by the progressive degeneration of the retina …
Lutein acts via multiple antioxidant pathways in the photo-stressed retina
M Kamoshita, E Toda, H Osada, T Narimatsu… - Scientific reports, 2016 - nature.com
Lutein slows the progression of age-related macular degeneration (AMD), a leading cause
of blindness in ageing societies. However, the underlying mechanisms remain elusive …
of blindness in ageing societies. However, the underlying mechanisms remain elusive …
[HTML][HTML] Blue light-induced inflammatory marker expression in the retinal pigment epithelium-choroid of mice and the protective effect of a yellow intraocular lens …
T Narimatsu, K Negishi, S Miyake, M Hirasawa… - Experimental eye …, 2015 - Elsevier
Oxidative stress in the retinal pigment epithelium (RPE) is a well-accepted pathogenic
change in vision-threatening diseases such as age-related macular degeneration. One …
change in vision-threatening diseases such as age-related macular degeneration. One …
The involvement of the oxidative stress in murine blue LED light-induced retinal damage model
M Nakamura, Y Kuse, K Tsuruma… - Biological and …, 2017 - jstage.jst.go.jp
The aim of study was to establish a mouse model of blue light emitting diode (LED) light-
induced retinal damage and to evaluate the effects of the antioxidant N-acetylcysteine …
induced retinal damage and to evaluate the effects of the antioxidant N-acetylcysteine …
Long-chain polyunsaturated fatty acids and their metabolites regulate inflammation in age-related macular degeneration
J Ren, A Ren, X Deng, Z Huang, Z Jiang… - Journal of …, 2022 - Taylor & Francis
Age-related macular degeneration (AMD) is a blinding eye disease, whose incidence
strongly increases with ages. The etiology of AMD is complex, including aging, abnormal …
strongly increases with ages. The etiology of AMD is complex, including aging, abnormal …
Editor's highlight: periodic exposure to smartphone-mimic low-luminance blue light induces retina damage through Bcl-2/BAX-dependent apoptosis
CH Lin, MR Wu, CH Li, HW Cheng… - Toxicological …, 2017 - academic.oup.com
Blue light-induced phototoxicity plays an important role in retinal degeneration and might
cause damage as a consequence of smartphone dependency. Here, we investigated the …
cause damage as a consequence of smartphone dependency. Here, we investigated the …
Neuroprotective effect of bilberry extract in a murine model of photo-stressed retina
H Osada, T Okamoto, H Kawashima, E Toda… - PLoS …, 2017 - journals.plos.org
Excessive exposure to light promotes degenerative and blinding retinal diseases such as
age-related macular degeneration and retinitis pigmentosa. However, the underlying …
age-related macular degeneration and retinitis pigmentosa. However, the underlying …
Splenic monocytes drive pathogenic subretinal inflammation in age-related macular degeneration
C Roubeix, C Nous, S Augustin, KE Ronning… - Journal of …, 2024 - Springer
Age-related macular degeneration (AMD) is invariably associated with the chronic
accumulation of activated mononuclear phagocytes in the subretinal space. The …
accumulation of activated mononuclear phagocytes in the subretinal space. The …