Sex differences in anxiety and depression: circuits and mechanisms

DA Bangasser, A Cuarenta - Nature Reviews Neuroscience, 2021 - nature.com
Epidemiological sex differences in anxiety disorders and major depression are well
characterized. Yet the circuits and mechanisms that contribute to these differences are …

Oxytocin, vasopressin, and social behavior: from neural circuits to clinical opportunities

N Rigney, GJ de Vries, A Petrulis, LJ Young - Endocrinology, 2022 - academic.oup.com
Oxytocin and vasopressin are peptide hormones secreted from the pituitary that are well
known for their peripheral endocrine effects on childbirth/nursing and blood pressure/urine …

Social anxiety disorder-associated gut microbiota increases social fear

NL Ritz, M Brocka, MI Butler… - Proceedings of the …, 2024 - National Acad Sciences
Social anxiety disorder (SAD) is a crippling psychiatric disorder characterized by intense
fear or anxiety in social situations and their avoidance. However, the underlying biology of …

Roles of oxytocin in stress responses, allostasis and resilience

Y Takayanagi, T Onaka - International journal of molecular sciences, 2021 - mdpi.com
Oxytocin has been revealed to work for anxiety suppression and anti-stress as well as for
psychosocial behavior and reproductive functions. Oxytocin neurons are activated by …

Detection, processing and reinforcement of social cues: regulation by the oxytocin system

R Menon, ID Neumann - Nature Reviews Neuroscience, 2023 - nature.com
Many social behaviours are evolutionarily conserved and are essential for the healthy
development of an individual. The neuropeptide oxytocin (OXT) is crucial for the fine-tuned …

Neural circuits of social behaviors: Innate yet flexible

D Wei, V Talwar, D Lin - Neuron, 2021 - cell.com
Social behaviors, such as mating, fighting, and parenting, are fundamental for survival of any
vertebrate species. All members of a species express social behaviors in a stereotypical and …

The multiple faces of the oxytocin and vasopressin systems in the brain

V Grinevich, M Ludwig - Journal of neuroendocrinology, 2021 - Wiley Online Library
Classically, hypothalamic neuroendocrine cells that synthesise oxytocin and vasopressin
were categorised in two major cell types: the magnocellular and parvocellular neurones. It …

Defining valid chronic stress models for depression with female rodents

J Lopez, RC Bagot - Biological psychiatry, 2021 - Elsevier
Women are twice as likely to experience depression than men, yet until recently, preclinical
studies in rodents have focused almost exclusively on males. As interest in sex differences …

Consequences of pandemic-associated social restrictions: Role of social support and the oxytocin system

K Gryksa, ID Neumann - Psychoneuroendocrinology, 2022 - Elsevier
During pandemics, governments take drastic actions to prevent the spreading of the
disease, as seen during the present COVID-19 crisis. Sanctions of lockdown, social …

Coordination of social behaviors by the bed nucleus of the stria terminalis

ME Flanigan, TL Kash - European Journal of Neuroscience, 2022 - Wiley Online Library
The bed nucleus of the stria terminalis (BNST) is a sexually dimorphic, neuropeptide‐rich
node of the extended amygdala that has been implicated in responses to stress, drugs of …