Protective efficacy of malaria case management for preventing malaria mortality in children: a systematic review for the Lives Saved Tool

J Thwing, TP Eisele, RW Steketee - BMC Public Health, 2011 - Springer
Abstract Background The Lives Saved Tool (LiST) model was developed to estimate the
impact of the scale-up of child survival interventions on child mortality. New advances in …

The effect of varying analytical methods on estimates of anti-malarial clinical efficacy

WJ Verret, G Dorsey, F Nosten, RN Price - Malaria Journal, 2009 - Springer
Background Analytical approaches for the interpretation of anti-malarial clinical trials vary
considerably. The aim of this study was to quantify the magnitude of the differences between …

Cardiac Conduction Safety during Coadministration of Artemether‐Lumefantrine and Lopinavir/Ritonavir in HIV‐Infected Ugandan Adults

P Byakika-Kibwika, M Lamorde, P Lwabi… - Chemotherapy …, 2011 - Wiley Online Library
Background. We aimed to assess cardiac conduction safety of coadministration of the
CYP3A4 inhibitor lopinavir/ritonavir (LPV/r) and the CYP3A4 substrate artemether …

Process Development for the Manufacture of the Antimalarial Amodiaquine Dihydrochloride Dihydrate

M Gohain, MS Malefo, P Kunyane… - … Process Research & …, 2023 - ACS Publications
A robust process for the manufacture of the active pharmaceutical ingredient (API)
amodiaquine dihydrochloride dihydrate (ADQ, 3), an important antimalarial, is reported. The …

In vitro antiplasmodial and cyclin-dependent protein kinase (pfmrk) inhibitory activities of selected flavonoids in combination with chloroquine (CQ) and artemisinin

CC Wanjala, HM Akala, CN Waters, A Yenesew… - 2010 - repository.seku.ac.ke
In this study, we report in vitro chloroquine (CQ) and artemisinin combination studies of eight
flavonoids against Plasmodium falciparum strains. The flavonoids were previously isolated …

[HTML][HTML] Resistance to dihydroartemisinin

E Legrand, B Volney, JB Meynard… - Emerging Infectious …, 2007 - ncbi.nlm.nih.gov
9. Bresson JL, Perronne C, Launay O, Gerdil C, Saville M, Wood J, et al. Safety and
immunogenicity of an inactivated splitvirion influenza A/Vietnam/1194/2004 (H5N1) vaccine …

[图书][B] Improved malaria case management in under-fives in the era of artemisinin-based combination therapy in Tanzania

BE Ngasala - 2010 - openarchive.ki.se
Early parasite-based diagnosis of malaria prior to treatment is critical for rational drug use,
optimal outcome of febrile illness, patient adherence, prevention of parasite drug resistance …

Discovery of antimalarial drug artemisinin and beyond

W Mao, Y Zhang, A Zhang - Case studies in modern drug …, 2012 - Wiley Online Library
Throughout the history of the development of mankind, nature has played a central role
providing food and medicines. Plants, in particular, have made a significant contribution in …

Artesunate plus amodiaquine combination therapy: reviewing the evidence

GO Adjei, W Kudzi, A Dodoo… - Drug Development …, 2010 - Wiley Online Library
The combination of artesunate plus amodiaquine (AS/AQ) is, next to the fixed‐dose
combination of artemether‐lumefantrine, the most widely adopted artemisinin combination …

[HTML][HTML] Malaria: uncomplicated, caused by Plasmodium falciparum

D Taylor-Robinson, K Jones, P Garner… - BMJ clinical …, 2008 - ncbi.nlm.nih.gov
Conclusions In this systematic review, we present information relating to the effectiveness
and safety of the following interventions: amodiaquine plus sulfadoxine-pyrimethamine; …