Assessing the causal association between human blood metabolites and the risk of gout
Y Xie, Y Li, J Zhang, Y Chen, R Ren… - European Journal of …, 2024 - Wiley Online Library
Background The occurrence of gout is closely related to metabolism, but there is still a lack
of evidence on the causal role of metabolites in promoting or preventing gout. Methods We …
of evidence on the causal role of metabolites in promoting or preventing gout. Methods We …
[HTML][HTML] Reassessing Gout Management through the Lens of Gut Microbiota
J Demarquoy, O Dehmej - Applied Microbiology, 2024 - mdpi.com
Gout, recognized as the most common form of inflammatory arthritis, arises from the
accumulation of uric acid crystals, leading to intense pain, particularly in the big toe. This …
accumulation of uric acid crystals, leading to intense pain, particularly in the big toe. This …
[HTML][HTML] Epigenetic and Metabolic Regulation of Macrophages during Gout
I Cobo, J Murillo-Saich, M Alishala… - Gout, Urate, and Crystal …, 2023 - mdpi.com
The analysis of metabolite mediators has allowed a broader understanding of disease
mechanisms. Experimental evidence indicates that metabolic rewiring is a key feature of …
mechanisms. Experimental evidence indicates that metabolic rewiring is a key feature of …
Association between combined exposure to ambient air pollutants, genetic risk, and incident gout risk: A prospective cohort study in the UK Biobank
W Liu, L Ye, B Hua, Y Yang, Z Dong, Y Jiang… - Seminars in Arthritis and …, 2024 - Elsevier
Background Limited research has been conducted on the association between long-term
exposure to air pollutants and the incidence of gout. Objectives This study aims to assess …
exposure to air pollutants and the incidence of gout. Objectives This study aims to assess …
Purification, characterization and anti-hyperuricemic mechanism of novel xanthine oxidase inhibitory peptides from tea (Camellia sinensis L.) protein
F Ma, S Sun, H Ye, Z Zhang, Q Chen, S Yin, Y Cao… - Food Bioscience, 2024 - Elsevier
In this study, two novel xanthine oxidase inhibitory peptides, PDEAVAYG (820.3602 Da) and
IAAGLQNTG (843.4450 Da), were purified and identified from tea protein hydrolysate, and …
IAAGLQNTG (843.4450 Da), were purified and identified from tea protein hydrolysate, and …
[HTML][HTML] Interpretable machine learning framework to predict gout associated with dietary fiber and triglyceride-glucose index
S Cao, Y Hu - Nutrition & Metabolism, 2024 - Springer
Background Gout prediction is essential for the development of individualized prevention
and treatment plans. Our objective was to develop an efficient and interpretable machine …
and treatment plans. Our objective was to develop an efficient and interpretable machine …
[HTML][HTML] Serum metabolomic analyses reveal the potential metabolic biomarkers for prediction of amatoxin poisoning
Y Liu, S Li, Y Feng, Y Zhang, J Ouyang, S Li, J Wang… - Toxicon, 2023 - Elsevier
Amatoxin poisoning leads to over 90% of deaths in mushroom poisoning. The objective of
present study was to identify the potential metabolic biomarkers for early diagnosis of …
present study was to identify the potential metabolic biomarkers for early diagnosis of …
溶质载体家族2 成员12 干预尿酸诱导肾小管细胞的损伤
贺怡， 李晓林， 何金科， 蒋香菊， 梁美婷， 陈邬锦… - 中国组织工程研究, 2024 - cjter.com
溶质载体家族2 成员12 干预尿酸诱导肾小管细胞的损伤 Page 1 2076|中国组织工程研究|第28卷
|第13期|2024年5月 中国组织工程研究 Chinese Journal of Tissue Engineering Research …
|第13期|2024年5月 中国组织工程研究 Chinese Journal of Tissue Engineering Research …
[HTML][HTML] Antihyperuricemic and Nephroprotective Effects of the Total Flavonoids from Carya cathayensis Leaves (CCTF) in Potassium Oxonate/hypoxanthine-induced …
J Hao, F Zhou - Clinical Complementary Medicine and Pharmacology, 2023 - Elsevier
Background Abnormally high level of uric acid in the blood, defined as hyperuricemia (HUA),
increases the chance of developing various disorders, such as gout, hypertension, and …
increases the chance of developing various disorders, such as gout, hypertension, and …
Comorbidities confound metabolomics studies of human disease
M Jaagura, J Kronberg, A Reigo, O Aasmets… - 2024 - researchsquare.com
The co-occurrence of multiple chronic conditions, termed multimorbidity, presents an
expanding global health challenge, demanding effective diagnostics and treatment …
expanding global health challenge, demanding effective diagnostics and treatment …