Neural tube defects (NTDs), including anencephaly and spina bifida, arise from the failure of
neurulation during early embryonic development. Neural tube defects are common birth …

Neural tube defects (NTDs) refer to a cluster of neurodevelopmental conditions associated
with failure of neural tube closure during embryonic development. Worldwide prevalence of …

Hyperhomocysteinemia is a risk factor in neurodegeneration. It has been suggested that
apart from disturbances in methylation processes, the mechanisms of this effect may include …

Publisher Summary In recent times, there has been a tremendous expansion in knowledge
of Na+-dependent glutamate (Glu) transporters. A large family has been identified using …

Under pathological conditions, microglia, the resident CNS immune cells, become reactive
and release pro-inflammatory cytokines and neurotoxic factors. We investigated whether this …

Sodium‐dependent, high‐affinity glutamate transport is generally assumed to limit the
toxicity of glutamate in vivo and in vitro, but there is very little direct evidence to support this …

Pharmacological and molecular biological studies provide evidence for subtypes of sodium‐
dependent high‐affinity glutamate (Glu) transport in the mammalian CNS. At least some of …

The present study has examined whether epithelial cells could be a source of the inducible
form of nitric oxide synthase (iNOS) in the colon of rats challenged with E. coli …

The excitotoxic action of homocysteine and related sulphur-containing metabolites was
investigated in organotpyic cultures derived from rat brain cortex and hippocampus by …

The ability of two conformationally restricted analogues of L-glutamate to function as
nontransportable inhibitors of plasma membrane L-glutamate transport was investigated in …