Inhibitors of acetylcholinesterase and butyrylcholinesterase meet immunity

M Pohanka - International journal of molecular sciences, 2014 - mdpi.com
Acetylcholinesterase (AChE) inhibitors are widely used for the symptomatic treatment of
Alzheimer's disease and other dementias. More recent use is for myasthenia gravis. Many of …

Acetylcholinesterase inhibitors as Alzheimer therapy: from nerve toxins to neuroprotection

M Singh, M Kaur, H Kukreja, R Chugh, O Silakari… - European journal of …, 2013 - Elsevier
Acetylcholinesterase is a member of the α/β hydrolase protein super family, with a significant
role in acetylcholine-mediated neurotransmission. Research in the modulators of AChEs …

Acetylcholinesterase inhibitors: pharmacology and toxicology

MB Colovic, DZ Krstic… - Current …, 2013 - ingentaconnect.com
Acetylcholinesterase is involved in the termination of impulse transmission by rapid
hydrolysis of the neurotransmitter acetylcholine in numerous cholinergic pathways in the …

[HTML][HTML] Neuroprotective effects of ononin against the aluminium chloride-induced Alzheimer's disease in rats

X Chen, M Zhang, M Ahmed, KM Surapaneni… - Saudi journal of …, 2021 - Elsevier
Alzheimer's disease (AD) is a chronic neurodegenerative disease categorized by the
deficiency in the cognition and memory. Approximately 50 million peoples has the AD, which …

Exposure to multiple cholinergic pesticides impairs olfactory learning and memory in honeybees

SM Williamson, GA Wright - Journal of Experimental Biology, 2013 - journals.biologists.com
Pesticides are important agricultural tools often used in combination to avoid resistance in
target pest species, but there is growing concern that their widespread use contributes to the …

Alzheimer s disease and oxidative stress: a review

M Pohanka - Current medicinal chemistry, 2014 - ingentaconnect.com
Alzheimer´ s disease (AD) is a neurodegenerative disorder with no known cure and rapid
rise in incidence. The predominant cognitive impairment is currently treated using cognitive …

The multifactorial nature of Alzheimer's disease for developing potential therapeutics

M Carmo Carreiras, E Mendes… - Current topics in …, 2013 - ingentaconnect.com
Alzheimerβs disease (AD) is a multifactorial neurodegenerative disorder with several target
proteins contributing to its aetiology. Pathological, genetic, biochemical, and modeling …

AlzPlatform: an Alzheimer's disease domain-specific chemogenomics knowledgebase for polypharmacology and target identification research

H Liu, L Wang, M Lv, R Pei, P Li, Z Pei… - Journal of chemical …, 2014 - ACS Publications
Alzheimer's disease (AD) is one of the most complicated progressive neurodegeneration
diseases that involve many genes, proteins, and their complex interactions. No effective …

Potent acetylcholinesterase inhibitors: potential drugs for Alzheimer's disease

H Akıncıoğlu, İ Gülçin - Mini reviews in medicinal chemistry, 2020 - ingentaconnect.com
Alzheimer's disease (AD) is one of the cognitive or memory-related impairments occurring
with advancing age. Since its exact mechanism is not known, the full therapy has still not …

Fluorescent determination of butyrylcholinesterase activity and its application in biological imaging and pesticide residue detection

Q Zhang, C Fu, X Guo, J Gao, P Zhang, C Ding - ACS sensors, 2021 - ACS Publications
Butyrylcholinesterase (BChE) is an essential human cholinesterase relevant to liver
conditions and neurodegenerative diseases, which makes it a pivotal biomarker of health. It …