Schizophrenia is frequently a chronic and disabling disorder, characterized by
heterogeneous positive and negative symptom constellations. The objective of this review …

Background Although antipsychotic maintenance treatment is widely recommended to
prevent relapse in chronic psychoses, evidence-based guidelines do not provide clear …

Schizophrenia is a heterogeneous psychiatric disorder, which can severely impact social
and professional functioning. Epidemiological and clinical studies show that schizophrenia …

Background: Inflammation plays a major role in the onset and maintenance of
schizophrenia. The objective of the present work was to synthetize in a narrative review the …

Schizophrenia is characterized by positive, negative, cognitive, and affective symptoms.
Antipsychotic medications, which work by blocking the dopamine D 2 receptor, are the …

These updated guidelines from the British Association for Psychopharmacology replace the
original version published in 2011. They address the scope and targets of pharmacological …

Background Negative symptoms of schizophrenia are associated with adverse clinical
outcomes, but there are few effective treatments. We aimed to assess the effects of …

Objectives: Identify the appropriate indications for the various antipsychotic medications.
Summarize the mechanism of action of both first and second-generation antipsychotics …

With new data about different aspects of schizophrenia being continually generated, it
becomes necessary to periodically revisit exactly what we know. Along with a need to review …

People with psychotic disorders can show marked interindividual variations in the onset of
illness, responses to treatment and relapse, but they receive broadly similar clinical care …