Ten golden rules for optimal antibiotic use in hospital settings: the WARNING call to action

World Journal of Emergency Surgery, 2023 - Springer
Antibiotics are recognized widely for their benefits when used appropriately. However, they
are often used inappropriately despite the importance of responsible use within good clinical …

Microbial resistance to antibiotics and effective antibiotherapy

AA Chiș, LL Rus, C Morgovan, AM Arseniu, A Frum… - Biomedicines, 2022 - mdpi.com
Currently, the efficacy of antibiotics is severely affected by the emergence of the
antimicrobial resistance phenomenon, leading to increased morbidity and mortality …

ACG clinical guidelines: prevention, diagnosis, and treatment of Clostridioides difficile infections

CR Kelly, M Fischer, JR Allegretti… - Official journal of the …, 2021 - journals.lww.com
Clostridioides difficile infection occurs when the bacterium produces toxin that causes
diarrhea and inflammation of the colon. These guidelines indicate the preferred approach to …

Plasmid-mediated metronidazole resistance in Clostridioides difficile

IM Boekhoud, BVH Hornung, E Sevilla… - Nature …, 2020 - nature.com
Metronidazole was until recently used as a first-line treatment for potentially life-threatening
Clostridioides difficile (CD) infection. Although cases of metronidazole resistance have been …

Clostridioides difficile infection: history, epidemiology, risk factors, prevention, clinical manifestations, treatment, and future options

S Di Bella, G Sanson, J Monticelli… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Clostridioides difficile infection (CDI) is one of the major issues in nosocomial infections.
This bacterium is constantly evolving and poses complex challenges for clinicians, often …

A Pharmacovigilance Study Regarding the Risk of Antibiotic-Associated Clostridioides difficile Infection Based on Reports from the EudraVigilance Database …

BI Vintila, AM Arseniu, C Morgovan, A Butuca, M Sava… - Pharmaceuticals, 2023 - mdpi.com
The Gram-positive anaerobic bacterium Clostridioides difficile (CD) can produce intense
exotoxins, contributing to nosocomial infections, and it is the most common cause of health …

[HTML][HTML] 临床重要耐药菌感染传播防控策略专家共识

杨启文, 吴安华, 胡必杰, 李六亿, 刘运喜… - 中国感染控制 …, 2021 - zggrkzzz.ijournals.cn
耐药菌的传播严重威胁人类健康, 目前耐药问题日益加剧, 给医疗卫生造成极大负担.
加强耐药菌感染的预防, 控制和诊疗能力建设是医疗机构防控耐药菌感染传播的重要内容 …

Gut microbiome and common variable immunodeficiency: few certainties and many outstanding questions

G Varricchi, R Poto, G Ianiro, A Punziano… - Frontiers in …, 2021 - frontiersin.org
Common variable immunodeficiency (CVID) is the most common symptomatic primary
antibody immunodeficiency, characterized by reduced serum levels of IgG, IgA, and/or IgM …

Recurrent Clostridioides difficile Infection: Current Clinical Management and Microbiome-Based Therapies

P Berry, S Khanna - BioDrugs, 2023 - Springer
Clostridioides difficile is one of the most important causes of healthcare-associated diarrhea.
The high incidence and recurrence rates of C. difficile infection, as well as its associated …

Gut Dysbiosis and Clostridioides difficile Infection in Neonates and Adults

IM Vasilescu, MC Chifiriuc, GG Pircalabioru… - Frontiers in …, 2022 - frontiersin.org
In this review, we focus on gut microbiota profiles in infants and adults colonized (CDC) or
infected (CDI) with Clostridioides difficile. After a short update on CDI epidemiology and …