Autophagy is a versatile degradation system for maintaining cellular homeostasis whereby
cytosolic materials are sequestered in a double-membrane autophagosome and …

Every cell must satisfy basic requirements for nutrient sensing, utilization and recycling
through macromolecular breakdown to coordinate programmes for growth, repair and stress …

Mitochondrial quality control is critical for cardiac homeostasis as these organelles are
responsible for generating most of the energy needed to sustain contraction. Dysfunctional …

Lysosomes are catabolic organelles that govern numerous cellular processes, including
macromolecule degradation, nutrient signalling and ion homeostasis. Aberrant changes in …

Since the discovery of lysosomes more than 70 years ago, much has been learned about
the functions of these organelles. Lysosomes were regarded as exclusively degradative …

Lysosomes are catabolic organelles that contribute to the degradation of intracellular
constituents through autophagy and of extracellular components through endocytosis …

Tumour cells under hypoxia tend to modulate the number and contents of extracellular
vesicles (EVs) to regulate the tumour microenvironment (TME) and thus promote tumour …

Lysosomes serve as degradation hubs for the turnover of endocytic and autophagic cargos,
which is essential for neuron function and survival. Deficits in lysosome function result in …

Quantum dots are nanocrystals with bright and tunable fluorescence. Due to their unique
property, quantum dots are sought after for their potential in several applications in …

Lysosome is one of the most crucial organelles in living systems. Lysosomal viscosity is an
important microenvironment parameter in lysosomes, which is closely related to the …