Photodynamic therapy (PDT) is a long known, FDA approved, and highly promising
therapeutic modality, which is still developing. Photosensitizers (PSs) are at the core of PDT …

Exosomes are small extracellular vesicles that originate from the intraluminal vesicles of
multivesicular bodies (MVBs). We previously reported that polarized Madin-Darby canine …

Ongoing efforts to generate a complete and accurate annotation of the genome have
revealed a significant blind spot for small proteins (< 100 amino acids) originating from short …

Macroautophagy is a health-modifying process of engulfing misfolded or aggregated
proteins or damaged organelles, coating these proteins or organelles into vesicles, fusion of …

Suppression of target of rapamycin complex 1 (TORC1) by rapamycin ameliorates aging in
diverse species. S6 kinase (S6K) is an essential mediator, but the mechanisms involved are …

Unhealthy lifestyle choices, poor diet, and aging can have negative influences on cognition,
gradually increasing the risk for mild cognitive impairment (MCI) and the continuum …

Plant reoviruses, transmitted only by insect vectors, seriously threaten global cereal
production. Understanding how insect vectors efficiently transmit the viruses is key to …

Cancer stem cell-like cells (CSCs) play an integral role in the heterogeneity, metastasis, and
treatment resistance of head and neck squamous cell carcinoma (HNSCC) due to their high …

The lysosome is an essential organelle to recycle cellular materials and maintain nutrient
homeostasis, but the mechanism to down-regulate its membrane proteins is poorly …

Microglial calcium signaling is rare in a baseline state but strongly engaged during early
epilepsy development. The mechanism (s) governing microglial calcium signaling are not …