Antimicrobial resistance is one of the major problems in current practical medicine. The
spread of genes coding for resistance determinants among bacteria challenges the use of …

Data on comprehensive population-based surveillance of antimicrobial resistance is lacking.
In low-and middle-income countries, the challenges are high due to weak laboratory …

The increase in antibiotic resistance is a global concern for human and animal health.
Resistant microorganisms can spread between food-producing animals and humans. The …

The transmission of pathogens from wild animals to humans is called “zoonotic spillover”.
Most human infectious diseases (60-75%) are derived from pathogens that originally …

Carbapenem resistance, mainly among Gram-negative pathogens, is an ongoing public-
health problem of global dimensions. This type of antimicrobial resistance, especially when …

Klebsiella pneumoniae is an important opportunistic pathogen that commonly causes
nosocomial infections and contributes to substantial morbidity and mortality. We sought to …

In this review, we summarize the current “state of the art” of carbapenem antibiotics and their
role in our antimicrobial armamentarium. Among the β-lactams currently available …

Carbapenems, once considered the last line of defense against of serious infections with
Enterobacteriaceae, are threatened with extinction. The increasing isolation of carbapenem …

During a Brazilian multicentric antimicrobial resistance surveillance study, colistin resistance
was investigated in 4,620 Enterobacteriaceae isolated from human, animal, food and …

The dissemination of carbapenem-resistant and third generation cephalosporin-resistant
pathogens is a critical issue that is no longer restricted to hospital settings. The rapid spread …