The treatment of bacterial infections suffers from two major problems: spread of multidrug-
resistant (MDR) or extensively drug-resistant (XDR) pathogens and lack of development of …

Urinary tract infections (UTIs) caused by Escherichia coli (E. coli) are the most common
types of infections in women. The antibiotic resistance of E. coli is increasing rapidly …

This is part of the series of practice guidelines commissioned by the Infectious Diseases
Society of America (IDSA) through its Practice Guidelines Committee. The purpose of this …

Synopsis Fosfomycin tromethamine is a phosphonic acid bactericidal agent with in vitro
activity against most urinary tract pathogens. It is particularly active against Escherichia coli …

Background Cystitis is a common infection. The alarmingly high resistance rates exhibited
by contemporary uropathogens necessitate the re-evaluation of old antibiotics. Objectives …

Fosfomycin is a broad-spectrum antibiotic discovered in Spain in 1969. It has bactericidal
activity against a wide range of bacteria, including gram-negative micro-organisms and …

Background Acute uncomplicated lower urinary tract infection (UTI) is one of the most
common problems for which young women seek medical attention. Objectives To compare …

Acute, uncomplicated urinary tract infections (UTI) are among the most commonly
encountered bacterial infections. Management of these infections has been made more …

This study is a comparison of the microbiological and clinical efficacy of single-dose
fosfomycin trometamol therapy and a 5 day course of trimethoprim in the treatment of …

Introduction The growing problem of antibacterial resistance resulted in an increased
interest in fosfomycin, especially its parenteral formulation. We reviewed fosfomycin safety …