Chronic ethanol consumption exacerbates liver injury following hemorrhagic shock: role of sinusoidal perfusion failure
I Bauer, M Bauer, BHJ Pannen, MJ Leinwand… - Shock, 1995 - journals.lww.com
Although the deleterious effect of chronic ethanol consumption on subsequent stressful
events has long been recognized, the pathophysiological mechanisms are incompletely …
events has long been recognized, the pathophysiological mechanisms are incompletely …
[HTML][HTML] The molecular basis of portal hypertension
DC Rockey - Transactions of the American Clinical and …, 2017 - ncbi.nlm.nih.gov
Cirrhosis leads to portal hypertension and vascular abnormalities in multiple vascular beds.
There is intense vasoconstriction in the liver and the kidneys, but also vasodilation in the …
There is intense vasoconstriction in the liver and the kidneys, but also vasodilation in the …
Eicosanoids in cirrhosis and portal hypertension
Y Birney, EM Redmond, JV Sitzmann… - Prostaglandins & other lipid …, 2003 - Elsevier
In the last decade, the knowledge of the pathogenesis of portal hypertension and cirrhosis
has increased dramatically. In portal hypertension, almost all the known vasoactive …
has increased dramatically. In portal hypertension, almost all the known vasoactive …
Importance of microcirculatory disturbances in the pathogenesis of pancreatitis
D Uhlmann, S Ludwig, F Geissler… - Zentralblatt für …, 2001 - thieme-connect.com
Zusammenfassung Die Kontrolle der Mikrozirkulation des Pankreas ist ein komplexer
physiologischer Prozess, der noch nicht vollständig verstanden wird. Der Blutfluss im …
physiologischer Prozess, der noch nicht vollständig verstanden wird. Der Blutfluss im …
Effect of selective blockade of endothelin ETB receptors on the liver dysfunction and injury caused by endotoxaemia in the rat
H Ruetten, C Thiemermann - British journal of pharmacology, 1996 - Wiley Online Library
1 We investigated the effects of the selective endothelin (ET) A receptor antagonist BQ485
and the selective ETB receptor antagonist BQ788 on circulatory failure, multiple organ …
and the selective ETB receptor antagonist BQ788 on circulatory failure, multiple organ …
Attenuation of proinflammatory gene expression and microcirculatory disturbances by endothelinA receptor blockade after orthotopic liver transplantation in pigs
D Uhlmann, G Gaebel, B Armann, S Ludwig, J Hess… - Surgery, 2006 - Elsevier
BACKGROUND: Endothelin-1 (ET-1), a very potent mediator of vasoconstriction, leads to
microcirculatory disturbances and release of proinflammatory cytokines under …
microcirculatory disturbances and release of proinflammatory cytokines under …
Endothelin-1 induces liver vasoconstriction through both ETA and ETB receptors
B Zhang, Y Calmus, L Wen, P Sogni, S Lotersztajn… - Journal of …, 1997 - Elsevier
Background/Aims: We investigated which endothelin receptors mediate the vasoconstrictive
effects of endothelin-1 on liver circulation. Methods: An isolated perfused rat liver model in …
effects of endothelin-1 on liver circulation. Methods: An isolated perfused rat liver model in …
Thromboxane A2 from Kupffer cells contributes to the hyperresponsiveness of hepatic portal circulation to endothelin-1 in endotoxemic rats
H Xu, K Korneszczuk, A Karaa, T Lin… - American Journal …, 2005 - journals.physiology.org
We examined the role of thromboxane A2 (TXA2) in LPS-induced hyperresponsiveness of
hepatic portal circulation to endothelins (ETs) and whether Kupffer cells are the primary …
hepatic portal circulation to endothelins (ETs) and whether Kupffer cells are the primary …
Potential therapeutic targets in cirrhotic cardiomyopathy
M Pozzi, L Ratti, C Guidi, M Milanese… - … Formerly Current Drug …, 2007 - ingentaconnect.com
Cirrhotic cardiomyopathy is a recently identified pathological condition defined as “a chronic
cardiac dysfunction in patients with cirrhosis characterized by blunted contractile …
cardiac dysfunction in patients with cirrhosis characterized by blunted contractile …