The tremendous heterogeneity of the human population presents a major obstacle in
understanding how autoimmune diseases like multiple sclerosis (MS) contribute to …

Objective To determine whether the ratio of cerebrospinal fluid (CSF) immunoglobulin kappa
to lambda light chains at time of multiple sclerosis (MS) diagnosis predicts disease …

The changing concepts in the neuropathology of acquired demy... : Current Opinion in Neurology
The changing concepts in the neuropathology of acquired demyelinating central nervous system …

Antibodies to different brain proteins have been recently found to be associated with an
increasing number of different autoimmune diseases. They need to penetrate the blood …

Abstract The sigma-1 (σ 1) receptor has been associated with regulation of intracellular Ca
2+ homeostasis, several cellular signaling pathways, and inter-organelle communication, in …

Background and Objectives To investigate the total circular RNA (circRNA) profile in patients
with relapsing-remitting multiple sclerosis (RRMS) and healthy controls (HCs). Methods …

Epstein-Barr virus (EBV) is the infectious agent that shows the strongest association with
multiple sclerosis (MS). EBV is a ubiquitous double stranded DNA herpes virus that …

CNS autoantigens conjugated to oxidized mannan (OM) induce antigen-specific T cell
tolerance and protect mice against autoimmune encephalomyelitis (EAE). To investigate …

The expanding therapeutic arsenal in multiple sclerosis (MS) has allowed for more effective
and personalized treatment, but the choice and management of disease-modifying therapies …

Multiple sclerosis is clinically characterized by relapses and remissions (relapsing-remitting
multiple sclerosis) that over time may evolve to a progressive course (secondary progressive …