Influenza remains one of the major public health concerns because it causes annual
epidemics and can potentially instigate a global pandemic. Numerous countermeasures …

Antibodies against viral pathogens represent promising therapeutic agents for the control of
infection, and their antiviral efficacy has been shown to require the coordinated function of …

Bioassays are the main tool to decipher bioactivities from natural resources thus their
selection and quality are critical for optimal bioprospecting. They are used both in the early …

Antibody responses against highly conserved epitopes on the stalk domain of influenza
virus hemagglutinin (HA) confer broad protection; however, such responses are limited. To …

Background Growing evidence suggests that sleep plays an important role in immunological
memory, including antibody responses to vaccination. However, much of the prior research …

Background The immunogenicity of the standard influenza vaccine is reduced in solid-organ
transplant (SOT) recipients, so new vaccination strategies are needed in this population …

Introduction Tick-borne encephalitis virus (TBEV) is one of the most relevant tick-transmitted
neurotropic arboviruses in Europe and Asia and the causative agent of tick-borne …

The continuous evolution of influenza A virus (IAV) requires the influenza vaccine
formulations to be updated annually to provide adequate protection. Recombinant protein …

This study reports on the immunogenicity and biodistribution of H5 hemagglutinin (HA)-
based self-amplifying (sa) mRNA vaccines in mice. Four sa-mRNA vaccines encoding either …

This project was initially conceived and directed by Y.-ML and MGRCI served as project
manager for all studies. EAH and Y.-ML designed experiments and analyzed data. CRW …