To determine the effects of a specific chromosomal lesion, the BCR-ABL translocation t (9:
22), in establishing DNA methylation profiles in cancer, we compared DNA methylation of …

Chronic myeloid leukemia (CML) is a malignant clonal blood disease that originates from a
pluripotent hematopoietic stem cell. The cytogenetic hallmark of CML, the Philadelphia …

El tratamiento de la leucemia granulocítica crónica ha evolucionado con gran rapidez:
desde los inicios relativamente modernos, cuando contábamos con el busulfán, hasta pasar …

Background Ablation of an oncogene or of the activity of the protein it encodes can result in
apoptosis and/or inhibit tumor cell proliferation. Therefore, if the oncogene or set of …

The twentieth century was a period of tremendous growth in knowledge of the causes and
natural history of many infectious diseases; this growth laid the foundations for considerable …

Preface emphasis has shifted in recent years to the notion that molecular defects acquired in
single haemopoietic stem cells may be the primary cause of these different but related …

Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by a
reciprocal translocation between the long arms of chromosomes 9 and 22 that results in …

Dermatologist's opinion is often sought for various types of drug reactions/side effects-
specially, if the effects are on skin, mucous membranes or genitals. Updating their …