Anticancer drug action on poly (A) polymerase activity and isoforms during HeLa and WISH cell apoptosis
NAA Balatsos, M Havredaki… - … International journal of …, 2000 - journals.sagepub.com
Poly (A) polymerase (PAP; EC 2.7. 7.19) catalyzes mRNA polyadenylation. Its activity and
isoform levels vary during cell cycle transformation and apoptosis. It has become widely …
isoform levels vary during cell cycle transformation and apoptosis. It has become widely …
Apoptosis and cancer therapy
M Reimann, CA Schmitt - Apoptosis, Cell Signaling, and Human Diseases …, 2007 - Springer
The observation that tumor development frequently is accompanied by apoptotic defects and
the meanwhile accepted view that the vast majority of conventional anticancer agents …
the meanwhile accepted view that the vast majority of conventional anticancer agents …
Oncogene-induced apoptosis in drug-resistant cells
HO Fearnhead, ME McCurrach, SW Lowe… - US Patent …, 2003 - Google Patents
The present invention relates to a method of identifying a compound (agent) which
modulates apoptosis in transformed cells. In one embodiment, the invention is a method of …
modulates apoptosis in transformed cells. In one embodiment, the invention is a method of …
[PDF][PDF] Split luciferase reporters of apoptosome formation: a bio-tool to identify new drug-like molecules
A Tashakor - 2019 - aran.library.nuigalway.ie
Formation of apoptosome, a key multiprotein complex in mitochondrial-mediated apoptosis,
is an essential step during normal development and deregulation of this event is associated …
is an essential step during normal development and deregulation of this event is associated …
SCREENING IRISH DEEP-SEA METABOLITES FOR ACTIVE COMPOUNDS AGAINST THE APOPTOSOME
RM Young, A Tashakor, M Decordi… - АРКТИЧЕСКИЕ …, 2018 - elibrary.ru
The deep-sea accounts for the majority the marine habitats. Despite this fact the contribution
of these deep-sea dwelling organisms to marine biodiscovery is greatly un-derrepresented …
of these deep-sea dwelling organisms to marine biodiscovery is greatly un-derrepresented …
[PDF][PDF] Role of c-Jun in the regulation of tumor suppressor p53 homologue, p73
L BOOMINATHAN - 2005 - core.ac.uk
Phd final 111 Page 1 ROLE OF c-JUN IN THE REGULATION OF TUMOR SUPPRESSOR p53
HOMOLOGUE, p73 L Boominathan M. Sc (Medical Biochemistry), Jawaharlal Institute of …
HOMOLOGUE, p73 L Boominathan M. Sc (Medical Biochemistry), Jawaharlal Institute of …
Cell-free assay using oncogene-induced apoptosis to identify inhibitors of apoptosis in drug-resistant cells
HO Fearnhead, ME McCurrach, SW Lowe… - US Patent …, 2003 - Google Patents
The present invention relates to a method of identifying a compound (agent) which
modulates apoptosis in transformed cells. In one embodiment, the invention is a method of …
modulates apoptosis in transformed cells. In one embodiment, the invention is a method of …
Small peptides having apoptotic activities and their applications
P Despres, A Catteau - US Patent 7,108,995, 2006 - Google Patents
The present invention relates to nine residue peptides (M 32-40) from flavivirus M
ectodomain able to modulate specifically the apoptotic activity of diverse flavivirus, to …
ectodomain able to modulate specifically the apoptotic activity of diverse flavivirus, to …
[PDF][PDF] ILP-2 Molecular Cloning of
MATERIALS AND METHODS Molecular cloning and characterization of ILP-2.
Combinations of oligonucleotides which collectively span the ILP-1 gene were tested in …
Combinations of oligonucleotides which collectively span the ILP-1 gene were tested in …
[PDF][PDF] Interactions in the Active Site Loops are Important for Maintaining the Active Site Environment of (Pro) caspase-3
B Feeney - 2004 - repository.lib.ncsu.edu
Apoptosis is obligatory to development and in maintaining the vital balance between cell
growth and death. Commitment to apoptosis involves a proteolytic cascade by a family of …
growth and death. Commitment to apoptosis involves a proteolytic cascade by a family of …