How I treat adult T-cell leukemia/lymphoma

LB Cook, AA Phillips - Blood, The Journal of the American …, 2021 - ashpublications.org
Adult T-cell leukemia/lymphoma (ATL) is a highly aggressive T-cell malignancy that arises in
a proportion of individuals who are long-term carriers of human T-lymphotropic virus type 1 …

CCR4 as a therapeutic target for cancer immunotherapy

O Yoshie - Cancers, 2021 - mdpi.com
Simple Summary CCR4 is a chemokine receptor selectively expressed on normal T cell
subsets such as type 2 helper T cells, skin-homing T cells and regulatory T cells, and on skin …

Prevalence of human T-lymphotropic virus type 1 and 2 (HTLV-1/-2) infection in pregnant women in Brazil: a systematic review and meta-analysis

BA Vieira, AB Bidinotto, WJ Dartora, LG Pedrotti… - Scientific reports, 2021 - nature.com
Human T-lymphotropic virus type 1 (HTLV-1) infection may cause serious disease, while
pathogenicity of HTLV-2 is less certain. There are no screening or surveillance programs for …

Natural selection signatures in the Hondo and Ryukyu Japanese subpopulations

X Liu, M Matsunami, M Horikoshi, S Ito… - Molecular Biology …, 2023 - academic.oup.com
Natural selection signatures across Japanese subpopulations are under-explored. Here we
conducted genome-wide selection scans with 622,926 single nucleotide polymorphisms for …

HTLV-1 persistence and the oncogenesis of adult T-cell leukemia/lymphoma

CRM Bangham - Blood, The Journal of the American Society of …, 2023 - ashpublications.org
Human T-cell leukemia virus type I (HTLV-1) causes adult T-cell leukemia/lymphoma (ATL)
in 5% of infected people with a decades-long latency. Charles RM Bangham reviews the …

Updates on HTLV-1 uveitis

K Kamoi, T Watanabe, K Uchimaru, A Okayama, S Kato… - Viruses, 2022 - mdpi.com
HTLV-1 uveitis (HU) is the third clinical entity to be designated as an HTLV-1-associated
disease. Although HU is considered to be the second-most frequent HTLV-1-associated …

Cost-effectiveness of human T-cell leukemia virus type 1 (HTLV-1) antenatal screening for prevention of mother-to-child transmission

A Kowada - PLoS neglected tropical diseases, 2023 - journals.plos.org
Background Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia-
lymphoma (ATL) and HTLV-1-associated myelopathy-tropical spastic paraparesis …

Antitumor effects of chloroquine/hydroxychloroquine mediated by inhibition of the NF-κB signaling pathway through abrogation of autophagic p47 degradation in adult …

YR Fauzi, S Nakahata, S Chilmi, T Ichikawa… - PLoS …, 2021 - journals.plos.org
Adult T-cell leukemia/lymphoma (ATLL) originates from human T-cell leukemia virus type 1
(HTLV-1) infection due to the activation of the nuclear factor-κB (NF-κB) signaling pathway to …

Lower prevalence of anti‐HTLV‐1 as expected by previous models among first‐time blood donors in Japan

M Satake, Y Sagara, I Hamaguchi - Journal of Medical Virology, 2023 - Wiley Online Library
An estimated 1.08 million carriers of human T‐lymphotropic virus 1 (HTLV‐1) were living in
Japan in 2006–2007. Since that study, new data on horizontal infection, nationwide …

Clinicopathological definition, management and prognostic value of mogamulizumab‐associated rash and other cutaneous events: A systematic review

G Avallone, G Roccuzzo, A Pileri… - Journal of the …, 2024 - Wiley Online Library
Mogamulizumab is a first‐in‐class IgG1k monoclonal antibody that selectively targets the
chemokine receptor type 4. The drug has received Food and Drug administration …