Research progress of natural Matrine compounds and synthetic Matrine derivatives

J Li, S Wei, D Marabada, Z Wang, Q Huang - Molecules, 2023 - mdpi.com
Matrine is a quinoline alkaloid extracted and separated from the dried root, fruit, and other
parts of the plant Sophora flavescens using an organic solvent. Matrine exhibits a variety of …

Sophflarine A, a novel matrine-derived alkaloid from Sophora flavescens with therapeutic potential for non-small cell lung cancer through ROS-mediated pyroptosis …

D Luo, X Dai, H Tian, C Fan, H Xie, N Chen, J Wang… - Phytomedicine, 2023 - Elsevier
Background Novel compounds and more efficient treatment options are urgently needed for
the treatment of non-small cell lung cancer (NSCLC). The decoction of Sophora flavescens …

Comprehensive investigation of the content and the origin of matrine-type alkaloids in Chinese honeys

Z Wang, T Zu, X Huang, X Jiang, G Jia, J Xu, Z Cui… - Food Chemistry, 2023 - Elsevier
Abstract A HPLC-MS/MS method for simultaneous determination of four matrine-type
alkaloids (matrine, oxymatrine, sophocarpine and sophoridine) in honey was established …

Undescribed matrine-type alkaloids from Sophora alopecuroides with anti-inflammatory activity

D Luo, JW Zou, JH Wang, H Tian, HY Xie, TX Zhu… - Phytochemistry, 2024 - Elsevier
A phytochemical investigation on the alkaloid fractions of Sophora alopecuroides L. led to
the production of 11 undescribed matrine-type alkaloids, sophaloseedlines I–S (1− 11), 12 …

Isosteroidal Alkaloids from Fritillaria verticillata Willd. and Their NMR Spectroscopic Characteristics

N Ma, YJ Wang, G Chen, CR Meng… - Chinese Journal of …, 2022 - Wiley Online Library
Comprehensive Summary Chemical investigation of Fritillaria verticillata Willd. led to the
isolation of eight novel isosteroidal alkaloids (1—4, 6, 9—11) and four known alkaloids (5, 7 …

Atropisomeric 9, 10-dihydrophenanthrene/bibenzyl trimers with anti-inflammatory and PTP1B inhibitory activities from Bletilla striata

M Sun, X Ma, S Shao, J Jiang, J Li, J Tian… - Organic & …, 2022 - pubs.rsc.org
Two pairs of novel trimeric dihydrophenanthrene–bibenzyl–dihydrophenanthrene
enantiomers (1 and2), the first examples of a dihydrophenanthrene dimer linked to a …

Matrine attenuates bovine mammary epithelial cells inflammatory responses induced by Streptococcus agalactiae through inhibiting NF-κB and MAPK signaling …

L Li, H Niu, J Zhan, Y Tu, L Jiang, Y Zhao - International …, 2022 - Elsevier
Streptococcus agalactiae is one of the main pathogens associated with bovine mastitis. The
invasion of S. agalactiae in bovine mammary epithelial cells (BMECs) has been implicated …

Three new quinolizidine alkaloids from the roots of Sophora tonkinensis

Q An, J Zhang, P Zhang, L Chen, P Yi… - Journal of Asian …, 2024 - Taylor & Francis
Abstract Three new quinolizidine alkaloids (1− 3), including one new naturally isoflavone
and cytisine polymer (3), along with 6 known ones were isolated from the ethanol extract of …

Two new isoflavones from the roots of Sophora tonkinensis

DJ Chen, S Yuan, P Zhang, Q An, JB Zou… - Journal of Asian …, 2023 - Taylor & Francis
Abstract Two new isoflavones (1 and 2), as well as eight known ones were isolated from the
roots of Sophora tonkinensis Gagnep. Compound 1 represents an unprecedented …

Impacts of Climate Change on the Habitat Suitability and Natural Product Accumulation of the Medicinal Plant Sophora alopecuroides L. Based on the MaxEnt Model

W Rong, X Huang, S Hu, X Zhang, P Jiang, P Niu, J Su… - Plants, 2024 - mdpi.com
Sophora alopecuroides L., a perennial herb in the arid and semi-arid regions of northwest
China, has the ecological functions of windbreaking and sand fixation and high medicinal …