[HTML][HTML] Challenges in circulating tumor cell detection by the CellSearch system

KC Andree, G van Dalum, LWMM Terstappen - Molecular oncology, 2016 - Elsevier
Enumeration and characterization of circulating tumor cells (CTC) hold the promise of a real
time liquid biopsy. They are however present in a large background of hematopoietic cells …

Clinical applications of the CellSearch platform in cancer patients

S Riethdorf, L O'Flaherty, C Hille, K Pantel - Advanced drug delivery …, 2018 - Elsevier
Abstract The CellSearch® system (CS) enables standardized enrichment and enumeration
of circulating tumor cells (CTCs) that are repeatedly assessable via non-invasive “liquid …

Profiling circulating tumour cells and other biomarkers of invasive cancers

M Poudineh, EH Sargent, K Pantel… - Nature Biomedical …, 2018 - nature.com
During cancer progression, many tumours shed circulating tumour cells (CTCs) and other
biomarkers into the bloodstream. The analysis of CTCs offers the prospect of collecting a …

Preventing postoperative metastatic disease by inhibiting surgery-induced dysfunction in natural killer cells

LH Tai, CT De Souza, S Bélanger, L Ly, AA Alkayyal… - Cancer research, 2013 - AACR
Natural killer (NK) cell clearance of tumor cell emboli following surgery is thought to be vital
in preventing postoperative metastases. Using a mouse model of surgical stress, we …

Clinical indications for, and the future of, circulating tumor cells

DH Moon, DP Lindsay, S Hong, AZ Wang - Advanced drug delivery reviews, 2018 - Elsevier
Circulating tumor cells (CTCs) are cells that have detached from the primary tumor and
entered circulation with potential to initiate a site of metastasis. Currently, CTC detection …

Detection of circulating tumour cells in peripheral blood of patients with advanced non‐metastatic bladder cancer

M Rink, FKH Chun, S Minner, M Friedrich… - BJU …, 2011 - Wiley Online Library
What's known on the subject? and What does the study add? Circulating tumour cells (CTC)
have prognostic relevance for patients with different metastatic carcinomas. Detection of …

[HTML][HTML] Liquid biopsy in urothelial carcinoma: Detection techniques and clinical applications

S Wu, R Li, Y Jiang, J Yu, J Zheng, Z Li, M Li… - Biomedicine & …, 2023 - Elsevier
The types of urothelial carcinoma (UC) include urothelial bladder cancer and upper tract
urothelial carcinoma. Current diagnostic techniques cannot meet the needs of patients …

Detection of circulating tumor cells in metastatic and clinically localized urothelial carcinoma

TW Flaig, S Wilson, A van Bokhoven, M Varella-Garcia… - Urology, 2011 - Elsevier
OBJECTIVE: To examine the incidence and prognostic value of circulating tumor cells
(CTCs) in urothelial cancer (UC). The detection of CTCs is prognostic in several cancer …

Diagnostic value of circulating tumor cell detection in bladder and urothelial cancer: systematic review and meta-analysis

P Msaouel, M Koutsilieris - BMC cancer, 2011 - Springer
Background The diagnostic value and prognostic significance of circulating tumor cell (CTC)
detection in patients with bladder cancer is controversial. We performed a meta-analysis to …

[HTML][HTML] In vitro culturing of viable circulating tumor cells of urinary bladder cancer

M Cegan, K Kolostova, R Matkowski… - … journal of clinical and …, 2014 - ncbi.nlm.nih.gov
Objective: Approximately one third of patients diagnosed with muscle-invasive urinary
bladder cancer (UBC) have undetected metastases at the time of treatment of the primary …