Kidney diseases remain one of the leading causes of human death and have placed a
heavy burden on the medical system. Regulated cell death contributes to the pathology of a …

Ferroptosis is a form of regulated cell death that is initiated by excessive lipid peroxidation
that results in plasma membrane damage and the release of damage-associated molecular …

Since the discovery of ferroptosis, it has been postulated that this type of cell death could be
utilized in treatments for cancer. Unfortunately, several highly aggressive tumor models are …

Ferroptosis is a newly discovered form of programmed cell death caused by redox-active
iron-mediated lipid peroxidation. Ferroptosis exhibits a unique morphological phenotype …

Mercury chloride can cause severe liver injury, which involves multiple mechanisms.
Ferroptosis plays an important role in regulating the development and progression of liver …

Recently, we reported that N-acetyltransferase 10 (NAT10) regulates fatty acid metabolism
through ac4C-dependent RNA modification of key genes in cancer cells. During this work …

Drugs causing ferroptosis, iron-mediated cell death, represent promising tools for cancer
treatment. While exploring the effect of these drugs on breast cancer (BC), we found that a …

The adenosine monophosphate (AMP)-activated protein kinase (AMPK) sits at a central
node in the regulation of energy metabolism and tumor progression. AMPK is best known to …

Cancer cells often exhibit defects in the execution of cell death, resulting in poor clinical
outcomes for patients with many cancer types. Ferroptosis is a newly discovered form of …

Non-small cell lung cancer (NSCLC) poses a significant global health burden with
unsatisfactory survival rates, despite advancements in diagnostic and therapeutic …