Physical non-viral gene delivery methods for tissue engineering

AJ Mellott, ML Forrest, MS Detamore - Annals of biomedical engineering, 2013 - Springer
The integration of gene therapy into tissue engineering to control differentiation and direct
tissue formation is not a new concept; however, successful delivery of nucleic acids into …

Regulated non-viral gene delivery from coaxial electrospun fiber mesh scaffolds

A Saraf, LS Baggett, RM Raphael, FK Kasper… - Journal of Controlled …, 2010 - Elsevier
In an effort to add to the versatility of three-dimensional scaffolds for tissue engineering
applications, recent experimental designs are incorporating biological molecules such as …

A short review: Recent advances in electrospinning for bone tissue regeneration

SH Shin, O Purevdorj, O Castano… - Journal of tissue …, 2012 - journals.sagepub.com
Nanofibrous structures developed by electrospinning technology provide attractive
extracellular matrix conditions for the anchorage, migration, and differentiation of tissue …

Incorporating small molecules or biologics into nanofibers for optimized drug release: A review

I Sebe, P Szabó, B Kállai-Szabó, R Zelkó - International journal of …, 2015 - Elsevier
Over the past several decades, the formulation of novel nanofiber-based drug delivery
systems focusing on specific delivery purposes has been investigated worldwide with a …

Matrices and scaffolds for DNA delivery in tissue engineering

L De Laporte, LD Shea - Advanced drug delivery reviews, 2007 - Elsevier
Regenerative medicine aims to create functional tissue replacements, typically through
creating a controlled environment that promotes and directs the differentiation of stem or …

Electrospun nanostructured scaffolds for tissue engineering applications

A Martins, JV Araújo, RL Reis, NM Neves - 2007 - Future Medicine
Despite being known for decades (since 1934), electrospinning has emerged recently as a
very widespread technology to produce synthetic nanofibrous structures. These structures …

[PDF][PDF] Core-shell fibers for biomedical applications-a review

MF Elahi, W Lu, G Guoping, F Khan - J. Bioeng. Biomed. Sci, 2013 - researchgate.net
Now is the age of high-tech research and development. Different types of fibers have been
produced in the last decades for the benefit of human needs. Core-shell nanofibers are a …

Electrospun fibers with plasmid bFGF polyplex loadings promote skin wound healing in diabetic rats

Y Yang, T Xia, F Chen, W Wei, C Liu… - Molecular …, 2012 - ACS Publications
Deep or chronic skin wounds are difficult to heal spontaneously due to the lack of scaffold to
guide cell growth and reduced levels and activities of endogenous growth factors. Emulsion …

Electrospinning: processing technique for tissue engineering scaffolding

A Martins, RL Reis, NM Neves - International Materials …, 2008 - journals.sagepub.com
Electrospinning has attracted tremendous interest in the research community as a simple
and versatile technique to produce synthetic polymeric ultrafine fibres with diameters …

Fiber based approaches as medicine delivery systems

F Sharifi, AC Sooriyarachchi, H Altural… - ACS Biomaterials …, 2016 - ACS Publications
The goal of drug delivery is to ensure that therapeutic molecules reach the intended target
organ or tissue, such that the effectiveness of the drug is maximized. The efficiency of a drug …