RNA interference (RNAi) is a promising approach for cancer treatment. Site specific and
controlled delivery of RNAi could be beneficial to the patient, while at the same time …

Our expanding ability to handle the “literally invisible” building blocks of our world has
started to provoke a seismic shift on the technology, environment and health sectorsin our …

Electrospinning is a versatile technique that enables the development of nanofiber-based
scaffolds, from a variety of polymers that may have drug-release properties. Using …

Electrospinning is a technology that has been widely used as a novel method for the
generation of nano scale fibres. Electrospun fibres are used in a wide range of applications …

Modulation of gene expression via microRNAs (miRNAs) has been attractive as one of the
promising strategies to cope with cardiovascular diseases, and the target-delivery of …

The electrospinning of polymers has previously shown excellent potential for localised gene
therapy. Thus, it was proposed that for the first time, the cell-penetrating CHAT peptide could …

Incorporation of gene into electrospun nanofibers for localized gene transfection of target
cells represents a robust platform for tissue regeneration. In this study, a new twostep …

Gene delivery is a potent alternative in comparison with angiogenic growth factor delivery to
stimulate the growth of new blood vessels in tissue constructs. The combining of polymeric …

A metal stent that could elute plasmid DNA (pDNA) in a controlled manner for substrate-
mediated gene transfection was fabricated by first coating with hyaluronic acid (HA) and …

Successfully reconstructing bone and restoring its dynamic function represents a significant
challenge for medicine. Critical size defects (CSDs), resulting from trauma, tumor removal, or …