Acquired or congenital abnormalities may lead to urethral damage or loss, often requiring
surgical reconstruction. Urethrocutaneous fistula and strictures are common complications …

The electrospinning of polymers has previously shown excellent potential for localised gene
therapy. Thus, it was proposed that for the first time, the cell-penetrating CHAT peptide could …

The development of effective strategies for gene delivery is a critical goal in DNA-based
tissue engineering. Previously, our laboratory utilized the process of electrospinning to …

Localized delivery of drugs is an emerging field both with regards to drug delivery during
disease as well as in tissue engineering. Despite significant achievements made in the last …

Traditional cancer treatment faces the problems of limited therapeutic efficiency, severe
adverse reactions, and/or infection, bleeding, and tissue defects after tumor surgery …

Organic solvents offer a new approach to formulate DNA into novel structures suitable for
gene delivery. In this study, we examined the in situ behavior of DNA in N, N …

Pulsed laser deposition was proved as a suitable method for hydroxyapatite (HA) coating of
coaxial polyɛcaprolactone/polyvinylalcohol (PCL/PVA) nanofibers. The fibrous …

Due to their large active surface, high loading efficiency, and tunable dissolution profiles,
nanofibrous mats are often cited as promising drug carriers or antimicrobial membranes …

Microbicides are topically applied, user controlled dosage forms that are being developed to
prevent the transmission of HIV during coitus. Early candidates focused on coitally …

Gene therapy today is hampered by the need of a safe and efficient gene delivery system
that can provide a sustained therapeutic effect without cytotoxicity or unwanted immune …