Chronic obstructive pulmonary disease (COPD) is the end result of a series of dynamic and
cumulative gene–environment interactions over a lifetime. The evolving understanding of …

Bronchial asthma is a heterogeneous disease characterized by persistent respiratory system
inflammation, airway hyperreactivity, and airflow obstruction. Airway remodeling, defined as …

Hyperpolarized (ie, polarized far beyond the thermal equilibrium) nuclear spins can result in
the radiofrequency amplification by stimulated emission of radiation (RASER) effect. Here …

Background Microvascular abnormalities and impaired gas transfer have been observed in
patients with COVID-19. The progression of pulmonary changes in these patients remains …

Prone positioning is an immediately accessible, readily implementable intervention that was
proposed initially as a method for improvement in gas exchange> 50 years ago. Initially …

Pulmonary functional magnetic resonance imaging (PfMRI) provides a way to non-invasively
map and measure the spatial distribution of pulmonary ventilation, perfusion and gas …

Molecular imaging, including quantification and molecular interaction studies, plays a crucial
role in visualizing and analysing molecular events occurring within cells or organisms, thus …

Background: In 2008, a dedicated American Thoracic Society/European Respiratory Society
task force published a paper on the possible use and limitations of clinical outcomes and …

Functional lung imaging modalities such as hyperpolarized gas MRI ventilation enable
visualization and quantification of regional lung ventilation; however, these techniques …

Background Hyperpolarized gas MRI can quantify regional lung ventilation via biomarkers,
including the ventilation defect percentage (VDP). VDP is computed from segmentations …