Background White matter hyperintensities are an important marker of cerebral small vessel
disease. This disease burden is commonly described as hyperintense areas in the cerebral …

Cerebral small vessel disease (cSVD) refers to the age-dependent pathological processes
involving the brain small vessels and leading to vascular cognitive impairment, intracerebral …

Objective Choroid plexus (CP) is a key regulator in cerebrospinal fluid production, but its
contribution to glymphatic clearance function and association with white matter …

Alzheimer's disease (AD) is the most common cause of dementia, characterized by the
aggregation of amyloid-beta (Aβ) proteins into plaques. Individuals with AD frequently show …

White matter hyperintensities (WMH) are the most prevalent markers of cerebral small vessel
disease (SVD), which is the major vascular risk factor for dementia. Microvascular pathology …

Cerebral white matter rarefaction (CWMR) was considered by Binswanger and Alzheimer to
be due to cerebral arteriolosclerosis. Renewed attention came with CT and MR brain …

Background: Alzheimer's disease (AD) frequently co-occurs with other brain pathologies.
Recent studies suggest there may be a mechanistic link between AD and small vessel …

Alzheimer disease (AD) models are based on the notion that abnormal protein aggregation
is the primary event in AD, which begins a decade or longer prior to symptom onset, and …

BACKGROUND: Silent cerebral infarcts (SCI) in sickle cell anemia (SCA) are associated
with future strokes and cognitive impairment, warranting early diagnosis and treatment …

Background White matter hyperintensities (WMH) in subjects across the Alzheimer's disease
(AD) spectrum with minimal vascular pathology suggests that amyloid pathology—not just …