Comprehensive Review of Drug–Drug Interaction Prediction Based on Machine Learning: Current Status, Challenges, and Opportunities

NN Wang, B Zhu, XL Li, S Liu, JY Shi… - Journal of Chemical …, 2023 - ACS Publications
Detecting drug–drug interactions (DDIs) is an essential step in drug development and drug
administration. Given the shortcomings of current experimental methods, the machine …

A systematic review of graph neural network in healthcare-based applications: Recent advances, trends, and future directions

SG Paul, A Saha, MZ Hasan, SRH Noori… - IEEE …, 2024 - ieeexplore.ieee.org
Graph neural network (GNN) is a formidable deep learning framework that enables the
analysis and modeling of intricate relationships present in data structured as graphs. In …

Uncovering hidden therapeutic indications through drug repurposing with graph neural networks and heterogeneous data

A Ayuso-Muñoz, L Prieto-Santamaría… - Artificial Intelligence in …, 2023 - Elsevier
Drug repurposing has gained the attention of many in the recent years. The practice of
repurposing existing drugs for new therapeutic uses helps to simplify the drug discovery …

Learning motif-based graphs for drug–drug interaction prediction via local–global self-attention

Y Zhong, G Li, J Yang, H Zheng, Y Yu… - Nature Machine …, 2024 - nature.com
Unexpected drug–drug interactions (DDIs) are important issues for both pharmaceutical
research and clinical applications due to the high risk of causing severe adverse drug …

Advancing tunnel equipment maintenance through data-driven predictive strategies in underground infrastructure

X Zou, J Zeng, G Yan, KJ Mohammed, M Abbas… - Computers and …, 2024 - Elsevier
Urban tunnel infrastructure, crucial for societal well-being, depends on reliable Tunnel
Electromechanical Equipment (TEE), including ventilation, drainage, and lighting systems. A …

MathEagle: Accurate Prediction of Drug-Drug Interaction Events via Multi-head Attention and Heterogeneous Attribute Graph Learning

LX Hou, HC Yi, ZH You, SH Chen, J Zheng… - Computers in Biology …, 2024 - Elsevier
Background Drug-drug interaction events influence the effectiveness of drug combinations
and can lead to unexpected side effects or exacerbate underlying diseases, jeopardizing …

ReHoGCNES-MDA: prediction of miRNA-disease associations using homogenous graph convolutional networks based on regular graph with random edge sampler

Y Zhang, Y Chu, S Lin, Y Xiong… - Briefings in …, 2024 - academic.oup.com
Numerous investigations increasingly indicate the significance of microRNA (miRNA) in
human diseases. Hence, unearthing associations between miRNA and diseases can …

SSR-DTA: Substructure-aware multi-layer graph neural networks for drug-target binding affinity prediction

Y Liu, X Xia, Y Gong, B Song, X Zeng - Artificial Intelligence in Medicine, 2024 - Elsevier
Accurate prediction of drug-target binding affinity (DTA) is essential in the field of drug
discovery. Recently, scientists have been attempting to utilize artificial intelligence prediction …

A comprehensive survey of drug-target interaction analysis in allopathy and siddha medicine

E Uma, T Mala, AV Geetha, D Priyanka - Artificial Intelligence in Medicine, 2024 - Elsevier
Effective drug delivery is the cornerstone of modern healthcare, ensuring therapeutic
compounds reach their intended targets efficiently. This paper explores the potential of …

[HTML][HTML] Nutrition-Related Knowledge Graph Neural Network for Food Recommendation

W Ma, M Li, J Dai, J Ding, Z Chu, H Chen - Foods, 2024 - ncbi.nlm.nih.gov
Food recommendation systems are becoming increasingly vital in modern society, given the
fast-paced lifestyle and diverse dietary habits. Existing research and implemented solutions …