Cervical cancer is the third most common cancer in women worldwide, with concepts and
knowledge about its prevention and treatment evolving rapidly. Human papillomavirus …

Recent advances in neoantigen research have accelerated the development and regulatory
approval of tumor immunotherapies, including cancer vaccines, adoptive cell therapy and …

DNA mutations as a consequence of errors during DNA damage repair, replication, or
mitosis are the substrate for evolution. In multicellular organisms, mutations can occur in the …

Comprehensive identification of somatic structural variations (SVs) and understanding their
mutational mechanisms in cancer might contribute to understanding biological differences …

The causes of ovarian dysgenesis remain incompletely understood. Two sisters with XX
ovarian dysgenesis carried compound heterozygous truncating mutations in the BRCA2 …

Structural variations (SVs) are a key type of cancer genomic alterations, contributing to
oncogenesis and progression of many cancers, including colorectal cancer (CRC) …

Genetic variation originates from several types of spontaneous mutation, including single-
nucleotide substitutions, short insertions and deletions (indels), and larger structural …

We have used whole genome paired-end Illumina sequence data to identify tandem
duplications in 20 isofemale lines of Drosophila yakuba and 20 isofemale lines of D …

Cancer research is at a crossroads. Traditionally, cancer has been thought of as a disease
of gene mutation, where the stepwise accumulation of cancer gene mutations is the key, and …

In the recent decade, gut microbiota has received growing interest due to its role in human
health and disease. On the one hand, by utilizing the signaling pathways of the host and …