Ivermectin for preventing and treating COVID‐19

M Popp, M Stegemann, MI Metzendorf… - Cochrane Database …, 2021 - cochranelibrary.com
Background Ivermectin, an antiparasitic agent used to treat parasitic infestations, inhibits the
replication of viruses in vitro. The molecular hypothesis of ivermectin's antiviral mode of …

Targeting the NLRP3 inflammasome in cardiovascular diseases

S Toldo, E Mezzaroma, LF Buckley, N Potere… - Pharmacology & …, 2022 - Elsevier
The NACHT, leucine-rich repeat (LRR), and pyrin domain (PYD)-containing protein 3
(NLRP3) inflammasome is an intracellular sensing protein complex that plays a major role in …

Real-world effectiveness of early molnupiravir or nirmatrelvir–ritonavir in hospitalised patients with COVID-19 without supplemental oxygen requirement on admission …

CKH Wong, ICH Au, KTK Lau, EHY Lau… - The Lancet Infectious …, 2022 - thelancet.com
Background Data on the effectiveness of oral antivirals in patients with mild-to-moderate
COVID-19 are urgently needed. This retrospective cohort study aimed to evaluate the …

Distinct evolution of SARS-CoV-2 Omicron XBB and BA. 2.86/JN. 1 lineages combining increased fitness and antibody evasion

D Planas, I Staropoli, V Michel, F Lemoine… - Nature …, 2024 - nature.com
The unceasing circulation of SARS-CoV-2 leads to the continuous emergence of novel viral
sublineages. Here, we isolate and characterize XBB. 1, XBB. 1.5, XBB. 1.9. 1, XBB. 1.16. 1 …

Nirmatrelvir plus ritonavir for early COVID-19 in a large US health system: a population-based cohort study

S Dryden-Peterson, A Kim, AY Kim… - Annals of internal …, 2023 - acpjournals.org
Background: In the EPIC-HR (Evaluation of Protease Inhibition for Covid-19 in High-Risk
Patients) trial, nirmatrelvir plus ritonavir led to an 89% reduction in hospitalization or death …

Effect of early treatment with ivermectin among patients with Covid-19

G Reis, EASM Silva, DCM Silva… - … England Journal of …, 2022 - Mass Medical Soc
Background The efficacy of ivermectin in preventing hospitalization or extended observation
in an emergency setting among outpatients with acutely symptomatic coronavirus disease …

COVID-19 convalescent plasma for the treatment of immunocompromised patients: a systematic review and meta-analysis

JW Senefeld, M Franchini, C Mengoli… - JAMA Network …, 2023 - jamanetwork.com
Importance Patients who are immunocompromised have increased risk for morbidity and
mortality associated with coronavirus disease 2019 (COVID-19) because they less …

Proportion of asymptomatic infection and nonsevere disease caused by SARS‐CoV‐2 Omicron variant: a systematic review and analysis

W Yu, Y Guo, S Zhang, Y Kong, Z Shen… - Journal of medical …, 2022 - Wiley Online Library
SARS‐CoV‐2 Omicron variant seemed to cause milder disease compared to previous
predominated variants. We aimed to conduct a meta‐analysis to assess the pooled …

[HTML][HTML] Ivermectin for prevention and treatment of COVID-19 infection: a systematic review, meta-analysis, and trial sequential analysis to inform clinical guidelines

A Bryant, TA Lawrie, T Dowswell… - American journal of …, 2021 - journals.lww.com
Ivermectin for Prevention and Treatment of COVID-19 Infectio... : American Journal of
Therapeutics Ivermectin for Prevention and Treatment of COVID-19 Infection: A Systematic …

ESC guidance for the diagnosis and management of cardiovascular disease during the COVID-19 pandemic: part 2—care pathways, treatment, and follow-up

Cardiovascular Research, 2022 - academic.oup.com
Aims Since its emergence in early 2020, the novel severe acute respiratory syndrome
coronavirus 2 causing coronavirus disease 2019 (COVID-19) has reached pandemic levels …