In development of an embryo, healing of a wound, or progression of a carcinoma, a requisite
event is collective epithelial cellular migration. For example, cells at the advancing front of a …

The expansion of fluorescence bioimaging toward more complex systems and geometries
requires analytical tools capable of spanning widely varying timescales and length scales …

Plasma cells (PCs), the B lineage cells responsible for producing and secreting antibodies
(Abs), are critical cellular components of the humoral immune system. While most of the …

The phasor approach to fluorescence lifetime imaging, and more recently hyperspectral
fluorescence imaging, has increased the use of these techniques, and improved the ease …

Macrophage infiltration and recruitment in breast tumors has been correlated with poor
prognosis in breast cancer patients and has been linked to tumor cell dissemination. Much …

Mitochondrial dysfunction is implicated in most neurodegenerative diseases, including
Alzheimer's disease (AD). We here combined experimental and computational approaches …

Multiphoton tomography for in vivo high-resolution multidimensional imaging has been used
in clinical investigations and small animal studies. The novel femtosecond laser tomographs …

A method of rapidly differentiating lung tumor from healthy tissue is extraordinarily needed
for both the diagnosis and the intraoperative margin assessment. We assessed the ability of …

Oncogenic mutations drive anabolic metabolism, creating a dependency on nutrient influx
through transporters, receptors, and macropinocytosis. While sphingolipids suppress tumor …

Perfluoroalkyl and polyfluoroalkyl substances (PFASs) are synthetic fluorinated compounds
that are highly bioaccumulative and persistent organic pollutants. Perfluorooctanoic acid …