A method of rapidly differentiating lung tumor from healthy tissue is extraordinarily needed
for both the diagnosis and the intraoperative margin assessment. We assessed the ability of …

Automated computational analysis techniques utilizing machine learning have been
demonstrated to be able to extract more data from different imaging modalities compared to …

In the field of fluorescence microscopy, there is continued demand for dynamic technologies
that can exploit the complete information from every pixel of an image. One imaging …

Perfluoroalkyl and polyfluoroalkyl substances (PFASs) are synthetic fluorinated compounds
that are highly bioaccumulative and persistent organic pollutants. Perfluorooctanoic acid …

Sirtuin 1 (SIRT1) is an NAD+-dependent deacetylase that functions as metabolic sensor of
cellular energy and modulates biochemical pathways in the adaptation to changes in the …

The expansion of fluorescence bioimaging toward more complex systems and geometries
requires analytical tools capable of spanning widely varying timescales and length scales …

Purpose To measure penetration and metabolic effects of ion-stabilized, polar, 15 nm gold
nanoparticles in aqueous solution (AuNP-Aq) and sterically stabilized, non-polar, 6 nm gold …

Direct monitoring of cell death (ie, apoptosis and necrosis) during or shortly after treatment is
desirable in all cancer therapies to determine the outcome. Further differentiation of …

Intracellular endogenous fluorescent co-enzymes, reduced nicotinamide adenine
dinucleotide (NADH) and flavin adenine dinucleotide (FAD), play a pivotal role in cellular …

Background The majority of cancer cells have a unique metabolic requirement for
methionine that is not observed in normal, non-tumorigenic cells. This phenotype is …