Molecular mechanisms of transgenerational epigenetic inheritance
MH Fitz-James, G Cavalli - Nature Reviews Genetics, 2022 - nature.com
Increasing evidence indicates that non-DNA sequence-based epigenetic information can be
inherited across several generations in organisms ranging from yeast to plants to humans …
inherited across several generations in organisms ranging from yeast to plants to humans …
[PDF][PDF] Metabolic consequences of obesity and type 2 diabetes: Balancing genes and environment for personalized care
The prevalence of type 2 diabetes and obesity has risen dramatically for decades and is
expected to rise further, secondary to the growing aging, sedentary population. The strain on …
expected to rise further, secondary to the growing aging, sedentary population. The strain on …
Transgenerational inheritance of acquired epigenetic signatures at CpG islands in mice
Transgenerational epigenetic inheritance in mammals remains a debated subject. Here, we
demonstrate that DNA methylation of promoter-associated CpG islands (CGIs) can be …
demonstrate that DNA methylation of promoter-associated CpG islands (CGIs) can be …
How does epigenetics influence the course of evolution?
A Ashe, V Colot, BP Oldroyd - … transactions of the …, 2021 - royalsocietypublishing.org
Epigenetics is the study of changes in gene activity that can be transmitted through cell
divisions but cannot be explained by changes in the DNA sequence. Epigenetic …
divisions but cannot be explained by changes in the DNA sequence. Epigenetic …
An integrative framework for understanding the mechanisms and multigenerational consequences of transgenerational plasticity
AM Bell, JK Hellmann - Annual Review of Ecology, Evolution …, 2019 - annualreviews.org
Transgenerational plasticity (TGP) occurs when the environment experienced by a parent
influences the development of their offspring. In this article, we develop a framework for …
influences the development of their offspring. In this article, we develop a framework for …
Biological pathways for historical trauma to affect health: A conceptual model focusing on epigenetic modifications
AKS Conching, Z Thayer - Social Science & Medicine, 2019 - Elsevier
Despite their unique histories, environments, and lifestyles, historically subjugated
populations consistently show poorer health outcomes compared to the general population …
populations consistently show poorer health outcomes compared to the general population …
Limitations of cross‐and multigenerational plasticity for marine invertebrates faced with global climate change
Although cross generation (CGP) and multigenerational (MGP) plasticity have been
identified as mechanisms of acclimation to global change, the weight of evidence indicates …
identified as mechanisms of acclimation to global change, the weight of evidence indicates …
[HTML][HTML] Paternal contributions to offspring health: role of sperm small RNAs in intergenerational transmission of epigenetic information
U Sharma - Frontiers in cell and developmental biology, 2019 - frontiersin.org
The most fundamental process for the perpetuation of a species is the transfer of information
from parent to offspring. Although genomic DNA contributes to the majority of the …
from parent to offspring. Although genomic DNA contributes to the majority of the …
Real‐time genomics for One Health
The ongoing degradation of natural systems and other environmental changes has put our
society at a crossroad with respect to our future relationship with our planet. While the …
society at a crossroad with respect to our future relationship with our planet. While the …