HLA-G is a molecule that was first known to confer protection to the fetus from destruction by
the immune system of its mother, thus critically contributing to fetal–maternal tolerance. The …

HLA-G has a relevant role in immune response regulation. The overall structure of the HLA-
G coding region has been maintained during the evolution process, in which most of its …

Patients with COVID-19 predominantly have a respiratory tract infection and acute lung
failure is the most severe complication. While the molecular basis of SARS-CoV-2 …

Human leukocyte antigen G (HLA-G) belongs to the family of non-classical HLA class I
genes, located within the major histocompatibility complex (MHC). HLA-G has been the …

BACKGROUND Although the immune system intuitively must have an important role in
embryo implantation and in the achievement of a pregnancy, the molecular details have for …

HLA‐G is a nonclassical HLA class I molecule. In allogeneic situations such as pregnancy or
allograft transplantation, the expression of HLA‐G has been related to a better acceptance of …

We here review the current data on the role of HLA‐G in cancer based on recent findings of
an unexpected antitumor activity of HLA‐G in hematological malignancies. For the past …

Despite decades of research, the highly prevalent pregnancy complication
preeclampsia,“the disease of theories,” has remained an enigma. Indeed, the etiology of …

The non-classical HLA-G is a well-known immune-modulatory molecule. In physiological
condition, HLA-G surface expression is restricted to the maternal–fetal interface and to …

In several years after its discovery in the placenta, the human leukocyte antigen (HLA) class
Ib protein, HLA-G, was not given much attention, nor was it assigned great importance. As …