The Nrf2 in the pathophysiology of the intestine: Molecular mechanisms and therapeutic implications for inflammatory bowel diseases

M Piotrowska, M Swierczynski, J Fichna… - Pharmacological …, 2021 - Elsevier
Abstract Nrf2 (nuclear factor erythroid 2-related factor 2) is a stress-responsive transcription
factor, associated with cellular homeostasis. Under normal conditions Nrf2 is kept in the …

[HTML][HTML] The role and mechanism of flavonoid herbal natural products in ulcerative colitis

JC Xue, S Yuan, H Meng, XT Hou, J Li… - Biomedicine & …, 2023 - Elsevier
Ulcerative colitis (UC) is a chronic inflammatory disease of the intestine that presents
clinically with abdominal pain, mucopurulent stools, and posterior urgency. The lesions of …

Grape seed proanthocyanidin extract ameliorates dextran sulfate sodium-induced colitis through intestinal barrier improvement, oxidative stress reduction, and …

K Sheng, G Zhang, M Sun, S He, X Kong, J Wang… - Food & function, 2020 - pubs.rsc.org
It is widely believed that grape seed proanthocyanidin extract (GSPE) exerts antioxidant and
anti-inflammatory effects. Dietary supplementation with GSPE has been reported to alleviate …

Intestinal flora: a pivotal role in investigation of traditional Chinese medicine

X Li, D Wu, J Niu, Y Sun, Q Wang, B Yang… - The American Journal …, 2021 - World Scientific
Intestinal flora is essential for maintaining host health and plays a unique role in
transforming Traditional Chinese Medicine (TCM). TCM, as a bodyguard, has saved …

[HTML][HTML] Anti-inflammatory natural products modulate interleukins and their related signaling markers in inflammatory bowel disease: A systematic review

GR Gandhi, T Mohana, K Athesh, VE Hillary… - Journal of …, 2023 - Elsevier
This review aims to identify in vivo studies investigating the potential of plant substances and
their natural molecules in managing inflammatory bowel disease (IBD). Specifically, the …

Green Pea (Pisum sativum L.) Hull Polyphenol Extracts Ameliorate DSS-Induced Colitis through Keap1/Nrf2 Pathway and Gut Microbiota Modulation

F Guo, R Tsao, C Li, X Wang, H Zhang, L Jiang, Y Sun… - Foods, 2021 - mdpi.com
As a processing by-product, green pea hull (GPH) was found to be rich in phenolic
components in our previous studies. In this study, UHPLC-LTQ-OrbiTrap-MS (Ultra …

Anti-Inflammatory Effects of Mytilus coruscus Polysaccharide on RAW264.7 Cells and DSS-Induced Colitis in Mice

XW Xiang, R Wang, LW Yao, YF Zhou, PL Sun… - Marine Drugs, 2021 - mdpi.com
Considerable literature has been published on polysaccharides, which play a critical role in
regulating the pathogenesis of inflammation and immunity. In this essay, the anti …

Therapeutic potential of quercetin loaded nanoparticles: Novel insights in alleviating colitis in an experimental DSS induced colitis model

SI Khater, MM Lotfy, MN Alandiyjany, LS Alqahtani… - Biomedicines, 2022 - mdpi.com
Oxidative stress is considered the main etiologic factor involved in inflammatory bowel
disease (IBD). Integration of nanocarriers for natural therapeutic agents with antioxidant and …

Cannabidiol-loaded injectable chitosan-based hydrogels promote spinal cord injury repair by enhancing mitochondrial biogenesis

H Zhang, T Hu, M Xiong, S Li, WX Li, J Liu… - International Journal of …, 2022 - Elsevier
The treatment of traumatic spinal cord injury (SCI) remains challenging as the neuron
regeneration is impaired by irregular cavity and apoptosis. An injectable in situ gelling …

Traditional Chinese medicine and natural products: potential approaches for inflammatory bowel disease

S Yuan, Y Li, J Li, JC Xue, Q Wang, XT Hou… - Frontiers in …, 2022 - frontiersin.org
Inflammatory bowel disease (IBD) is a rare, recurrent, and intractable inflammation
obstruction of the stomach tract, usually accompanied by inflammation of cell proliferation …