Abstract Poly (lactic acid)(PLA) has become a “material of choice” in biomedical applications
for its ability to fulfill complex needs that typically include properties such as biocompatibility …

Surface modification and endothelialization of vascular biomaterials are common
approaches that are used to both resist the nonspecific adhesion of proteins and improve …

Blood-contacting surfaces of cardiovascular devices are not biocompatible for creating an
endothelial layer on them. Numerous research studies have mainly sought to modify these …

Abstract Three-dimensional (3D) monolithic structures (ie, aerogels/sponges/scaffolds)
assembled from fragmented electrospun nanofiber mats/membranes represent an emerging …

Small-diameter vascular grafts (SDVGs)(D< 6 mm) are increasingly needed in clinical
settings for cardiovascular disease, including coronary artery and peripheral vascular …

To date, a wide range of materials, from synthetic to natural or a mixture of these, has been
explored, modified, and examined as small-diameter tissue-engineered vascular grafts (SD …

A continuous electrospinning technique was applied to fabricate double layer tubular tissue
engineering vascular graft (TEVG) scaffold. The luminal layer was made from poly (ɛ …

Numerous clinical trials have indicated that an anti-platelet treatment can reduce the risk of
recurrent stroke events. Dipyridamole (DIP) is a pharmaceutical compound known to induce …

The inadequacies of the currently used small diameter, non-biodegradable synthetic grafts
prompt researchers to focus on the design parameters of vascular grafts. Since the purpose …

Coronary artery disease represents the most common type of heart disease and accounts for
about 7.4 million deaths worldwide in 2012 [1]. Prognoses indicate that annual mortality from …