The convergence of artificial intelligence (AI) and precision medicine promises to
revolutionize health care. Precision medicine methods identify phenotypes of patients with …

Neuropilins are transmembrane glycoproteins that play important roles in cardiovascular
and neuronal development, as well as in immunological system regulations. NRP1 functions …

Purpose Medulloblastoma, the most common primary pediatric malignant brain tumor,
originates in the posterior fossa of the brain. Pineoblastoma, which originates within the …

Motivation Medulloblastoma (MB) is a brain cancer predominantly arising in children.
Roughly 70% of patients are cured today, but survivors often suffer from severe sequelae …

Most cases of medulloblastoma (MB) occur in young children. While the overall survival rate
can be relatively high, current treatments combining surgery, chemo‐and radiotherapy are …

Purpose Pediatric brain cancer medulloblastoma (MB) standard-of-care results in numerous
comorbidities. MB is comprised of distinct molecular subgroups. Group 3 molecular …

Medulloblastomas (MBs) are malignant pediatric brain tumors that are molecularly and
clinically heterogenous. The application of omics technologies—mainly studying nucleic …

The thioredoxin (Trx) system is an important enzyme family that regulates cellular redox
homeostasis. Protein expression of Trx system family members has been assessed in …

Medulloblastoma is the most common embryonal tumor in children. The current standard of
care comprises surgical resection, radiation and chemotherapy. Patients are stratified into …

Simple Summary In the last decade, medulloblastoma entered the molecular era, with
progressive advances in the knowledge of the molecular biology of this rare tumor. These …