Extended Treatment with Micron-Size Oral Palmitoylethanolamide (PEA) in Chronic Pain: A Systematic Review and Meta-Analysis

V Schweiger, C Schievano, A Martini, L Polati… - Nutrients, 2024 - mdpi.com
Palmitoylethanolamide (PEA) emerged over the years as a promising approach in the
management of chronic pain. Despite the fact that the efficacy of micron-size PEA …

αO-Conotoxin GeXIVA [1, 2] Reduced Neuropathic Pain and Changed Gene Expression in Chronic Oxaliplatin-Induced Neuropathy Mice Model

H Wang, X Li, Y Qiao, M Wang, W Wang, JM McIntosh… - Marine Drugs, 2024 - mdpi.com
Chemotherapy-induced peripheral neuropathy (CIPN) is a dose-limiting painful neuropathy
that occurs commonly during cancer management, which often leads to the discontinuation …

New Insight into Neuropathic Pain: The Relationship between α7nAChR, Ferroptosis, and Neuroinflammation

F Luo, C Huang - International Journal of Molecular Sciences, 2024 - mdpi.com
Neuropathic pain, which refers to pain caused by a lesion or disease of the somatosensory
system, represents a wide variety of peripheral or central disorders. Treating neuropathic …

Interactions and Trends of Interleukins, PAI-1, CRP, and TNF-α in Inflammatory Responses during the Perioperative Period of Joint Arthroplasty: Implications for Pain …

AC Cocea, CI Stoica - Journal of Personalized Medicine, 2024 - mdpi.com
Inflammation during the perioperative period of joint arthroplasty is a critical aspect of patient
outcomes, influencing both the pathophysiology of pain and the healing process. This …

[PDF][PDF] Spasmolytic Activity, Anti-Inflammatory Potential, and Molecular Docking Studies of Anthranilic Acid Hybrids

M Milusheva, V Gledacheva, I Stefanova… - researchgate.net
Anthranilic acid and its analogs have an impressive biological profile; its structural nucleus
has been thoroughly studied for the development of pharmaceuticals. Due to the predicted …