A prefrontal–thalamo–hippocampal circuit for goal-directed spatial navigation

HT Ito, SJ Zhang, MP Witter, EI Moser, MB Moser - Nature, 2015 - nature.com
Spatial navigation requires information about the relationship between current and future
positions. The activity of hippocampal neurons appears to reflect such a relationship …

[HTML][HTML] Phase precession in the human hippocampus and entorhinal cortex

SE Qasim, I Fried, J Jacobs - Cell, 2021 - cell.com
Knowing where we are, where we have been, and where we are going is critical to many
behaviors, including navigation and memory. One potential neuronal mechanism underlying …

Locally ordered representation of 3D space in the entorhinal cortex

G Ginosar, J Aljadeff, Y Burak, H Sompolinsky, L Las… - Nature, 2021 - nature.com
As animals navigate on a two-dimensional surface, neurons in the medial entorhinal cortex
(MEC) known as grid cells are activated when the animal passes through multiple locations …

Time cells in the human hippocampus and entorhinal cortex support episodic memory

G Umbach, P Kantak, J Jacobs… - Proceedings of the …, 2020 - National Acad Sciences
The organization of temporal information is critical for the encoding and retrieval of episodic
memories. In the rodent hippocampus and entorhinal cortex, evidence accumulated over the …

Dopaminergic neurons promote hippocampal reactivation and spatial memory persistence

CG McNamara, Á Tejero-Cantero, S Trouche… - Nature …, 2014 - nature.com
We found that optogenetic burst stimulation of hippocampal dopaminergic fibers from
midbrain neurons in mice exploring novel environments enhanced the reactivation of …

Neurophysiological and computational principles of cortical rhythms in cognition

XJ Wang - Physiological reviews, 2010 - journals.physiology.org
Synchronous rhythms represent a core mechanism for sculpting temporal coordination of
neural activity in the brain-wide network. This review focuses on oscillations in the cerebral …

[HTML][HTML] Entorhinal-CA3 dual-input control of spike timing in the hippocampus by theta-gamma coupling

A Fernández-Ruiz, A Oliva, GA Nagy, AP Maurer… - Neuron, 2017 - cell.com
Theta-gamma phase coupling and spike timing within theta oscillations are prominent
features of the hippocampus and are often related to navigation and memory. However, the …

Brain rhythms and neural syntax: implications for efficient coding of cognitive content and neuropsychiatric disease.

G Buzsáki, BO Watson - Dialogues in clinical neuroscience, 2012 - Taylor & Francis
The perpetual activity of the cerebral cortex is largely supported by the variety of oscillations
the brain generates, spanning a number of frequencies and anatomical locations, as well as …

Reactivation predicts the consolidation of unbiased long-term cognitive maps

AD Grosmark, FT Sparks, MJ Davis, A Losonczy - Nature Neuroscience, 2021 - nature.com
Spatial memories that can last a lifetime are thought to be encoded during 'online'periods of
exploration and subsequently consolidated into stable cognitive maps through their …

[HTML][HTML] Neural syntax: cell assemblies, synapsembles, and readers

G Buzsáki - Neuron, 2010 - cell.com
A widely discussed hypothesis in neuroscience is that transiently active ensembles of
neurons, known as" cell assemblies," underlie numerous operations of the brain, from …