Functions of the neocortex depend on its bidirectional communication with the thalamus, via
cortico-thalamo-cortical (CTC) loops. Recent work dissecting the synaptic connectivity in …

Standard models of episodic memory focus on hippocampal–parahippocampal interactions,
with the neocortex supplying sensory information and providing a final repository of …

The hippocampus is crucial for episodic memory, but it is also involved in online prediction.
Evidence suggests that a unitary hippocampal code underlies both episodic memory and …

The retrosplenial cortex is reciprocally connected with multiple structures implicated in
spatial cognition, and damage to the region itself produces numerous spatial impairments …

It is still widely thought that cortical projections to distant brain areas derive by and large
from glutamatergic neurons. However, an increasing number of reports provide evidence …

After more than 80 years, Papez serial circuit remains a hugely influential concept, initially
for emotion, but in more recent decades, for memory. Here, we show how this circuit is …

Neuropsychiatric disorders are often accompanied by cognitive impairments/intellectual
disability (ID). It is not clear whether there are converging mechanisms underlying these …

Bouts of high frequency activity known as sharp wave ripples (SPW-Rs) facilitate
communication between the hippocampus and neocortex. However, the paths and …

The retrosplenial cortex (RC) is a brain structure crucial for spatial navigation and memory. It
contains neurons such as head direction cells, border cells, as well as other cells supporting …

The prefrontal cortex (PFC) has a complex relationship with the thalamus, involving many
nuclei which occupy predominantly medial zones along its anterior-to-posterior extent …