Thyroid hormones (THs), including T4 and T3, are produced and released by the thyroid
gland under the stimulation of thyroid-stimulating hormone (TSH). The homeostasis of THs is …

Background A single dose of potassium iodide (KI) is recommended to reduce the risk of
thyroid cancer during nuclear accidents. However in case of prolonged radioiodine …

Aim This study aimed at evaluating whether thyroid hormone treatment could improve
glycaemia and insulin response in alloxan‐induced diabetic rats by altering cytokine …

Adequate iodide supply and metabolism are essential for thyroid hormones synthesis. In
thyrocytes, iodide uptake is mediated by the sodium-iodide symporter, but several proteins …

Background: Iodine is essential for thyroid hormone synthesis and is an important regulator
of thyroid function. Chronic iodine deficiency leads to hypothyroidism, but iodine excess also …

Wolff-Chaikoff effect is characterized by the blockade of thyroid hormone synthesis and
secretion due to iodine overload. However, the regulation of monocarboxylate transporter 8 …

It is well known that excess iodide can lead to thyroid colloid retention, a classic
characteristic of iodide-induced goiter. However, the mechanism has not been fully …

Iodide (I−) is crucial to thyroid function, and its regulation in thyrocytes involves ion
transporters and reactive oxygen species (ROS). However, the extent of 2Cl−/H+ exchanger …

Iodine is required for the synthesis of the thyroid hormones. Recommended daily iodine
intake in adults is 150 μg daily, except in pregnant and lactating women who require higher …

Rapid actions of triiodothyronine (T3) on thyrotropin (TSH) synthesis and secretion have
been described in hypothyroid male rats. However, the molecular mechanisms remain …