MEG3, a significant long non-coding RNA (lncRNA), substantially functions in diverse
biological processes, particularly breast cancer (BC) development. Within the imprinting …

Pancreatic cancer (PC) is one of the most common malignancies. Surgical resection is a
potential curative approach for PC, but most patients are unsuitable for operations when at …

Esophageal squamous cell carcinoma (ESCC) is a deadly cancer with no clinically relevant
biomarkers for early detection. Here, we comprehensively characterized the transcriptional …

Biomarker discovery and development are popular for detecting the subtle diseases.
However, biomarkers are needed to be validated and approved, and even fewer are ever …

Head and neck cancer (HNC) is a prevalent and diverse group of malignancies with
substantial morbidity and mortality rates. Early detection and monitoring of HNC are crucial …

Liver cancer is one of the most common malignancies, with severe morbidity and mortality.
While considerable progress has been made in liver cancer treatment, the 5-year overall …

The incidence and mortality rates of cancer are increasing every year worldwide but the
survival rate of cancer patients is still unsatisfactory. Therefore, it is necessary to further …

Methylation of RNA plays an important role in cancer. Classical forms of such modifications
include N6-methyladenine (m6A), 5-methylcytosine (m5C), and N1-methyladenine (m1A) …

Cancer drug resistance remains a formidable challenge in modern oncology, necessitating
innovative therapeutic strategies. The convergence of intricate regulatory networks involving …

Next-generation sequencing has revealed that less than 2% of transcribed genes are
translated into proteins, with a large portion transcribed into noncoding RNAs (ncRNAs) …