Highly diastereoselective four-component synthesis of polysubstituted 2-piperidinones with three and four stereogenic centers

AN Vereshchagin, KA Karpenko, MN Elinson… - Research on Chemical …, 2020 - Springer
A novel four-component diastereoselective synthesis of polysubstituted 2-piperidinones is
reported. The Michael addition–Mannich cascade of benzylidenemalononitriles or …

Acid‐catalyzed recyclization of spiroindolinepyrano[3,2‐b]pyrans to 3,4‐dihydroquinolinone derivatives containing allomaltol fragment

CV Milyutin, AN Komogortsev… - Journal of …, 2023 - Wiley Online Library
For the first time, we developed a novel one‐step method for the synthesis of substituted 3, 4‐
dihydroquinolinones with allomaltol moiety. The suggested approach includes acid …

Crystal Structure of Nilotinib Hydrochloride Monohydrate According to Powder X-Ray Diffraction Data

AS Goloveshkin, ES Kulikova, RA Novikov… - Journal of Structural …, 2024 - Springer
The crystal structure of nilotinib hydrochloride monohydrate, being an active pharmaceutical
substance of the drug Tasigna for chronic myeloid leukemia, is determined by powder X-ray …

КРИСТАЛЛИЧЕСКОЕ СТРОЕНИЕ МОНОГИДРАТА ГИДРОХЛОРИДА НИЛОТИНИБА ПО ДАННЫМ ПОРОШКОВОЙ РЕНТГЕНОВСКОЙ ДИФРАКЦИИ

АС ГОЛОВЕШКИН, ЕС КУЛИКОВА… - ЖУРНАЛ …, 2024 - elibrary.ru
С помощью порошковой рентгеновской дифракции от источника синхротронного
излучения НИЦ «Курчатовский институт» установлено кристаллическое строение …