The effects of aging in the hippocampus and cognitive decline

LEB Bettio, L Rajendran, J Gil-Mohapel - Neuroscience & Biobehavioral …, 2017 - Elsevier
Aging is a natural process that is associated with cognitive decline as well as functional and
social impairments. One structure of particular interest when considering aging and …

[HTML][HTML] Rational design of boron nitride with different dimensionalities for sustainable applications

N Han, S Wang, AK Rana, S Asif, JJ Klemeš… - … and Sustainable Energy …, 2022 - Elsevier
The application of boron nitride (BN) nanomaterials in various fields received extensive
attention in the past decades, attributed to its extraordinary characteristics: high surface …

[HTML][HTML] Tropomyosin receptor kinase (TRK) biology and the role of NTRK gene fusions in cancer

A Amatu, A Sartore-Bianchi, K Bencardino… - Annals of …, 2019 - Elsevier
The tropomyosin receptor kinase (TRK) family of receptor tyrosine kinases are encoded by
NTRK genes and have a role in the development and normal functioning of the nervous …

Tanezumab for the treatment of pain from osteoarthritis of the knee

NE Lane, TJ Schnitzer, CA Birbara… - … England Journal of …, 2010 - Mass Medical Soc
Background Increased expression of nerve growth factor in injured or inflamed tissue is
associated with increased pain. This proof-of-concept study was designed to investigate the …

Biological hypotheses and biomarkers of bipolar disorder

E Sigitova, Z Fišar, J Hroudová… - Psychiatry and …, 2017 - Wiley Online Library
The most common mood disorders are major depressive disorders and bipolar disorders
(BD). The pathophysiology of BD is complex, multifactorial, and not fully understood …

[HTML][HTML] Therapeutic potential of Hericium erinaceus for depressive disorder

PS Chong, ML Fung, KH Wong, LW Lim - International journal of …, 2020 - mdpi.com
Depression is a common and severe neuropsychiatric disorder that is one of the leading
causes of global disease burden. Although various anti-depressants are currently available …

The neurotrophin family of neurotrophic factors: an overview

SD Skaper - Neurotrophic factors: Methods and protocols, 2012 - Springer
The neurotrophins are a family of closely related proteins that were first identified as survival
factors for sympathetic and sensory neurons and have since been shown to control a …

Neuronal cell cycle: the neuron itself and its circumstances

JM Frade, MC Ovejero-Benito - Cell cycle, 2015 - Taylor & Francis
Neurons are usually regarded as postmitotic cells that undergo apoptosis in response to cell
cycle reactivation. Nevertheless, recent evidence indicates the existence of a defined …

[HTML][HTML] Pleiotropic effects of BDNF on the cerebellum and hippocampus: Implications for neurodevelopmental disorders

S Camuso, P La Rosa, MT Fiorenza, S Canterini - Neurobiology of disease, 2022 - Elsevier
Brain-derived neurotrophic factor (BDNF) is one of the most studied neurotrophins in the
mammalian brain, essential not only to the development of the central nervous system but …

Cholinergic system during the progression of Alzheimer's disease: therapeutic implications

EJ Mufson, SE Counts, SE Perez… - Expert review of …, 2008 - Taylor & Francis
Alzheimer's disease (AD) is characterized by a progressive phenotypic downregulation of
markers within cholinergic basal forebrain (CBF) neurons, frank CBF cell loss and reduced …