The role of BDNF in experimental and clinical traumatic brain injury

D Gustafsson, A Klang, S Thams… - International journal of …, 2021 - mdpi.com
Traumatic brain injury is one of the leading causes of mortality and morbidity in the world
with no current pharmacological treatment. The role of BDNF in neural repair and …

Application of extracorporeal shock wave therapy in nervous system diseases: a review

J Guo, H Hai, Y Ma - Frontiers in Neurology, 2022 - frontiersin.org
Neurological disorders are one of the leading causes of morbidity and mortality worldwide,
and their therapeutic options remain limited. Recent animal and clinical studies have shown …

Neural stem cell delivery using brain-derived tissue-specific bioink for recovering from traumatic brain injury

M Bae, MK Ko, Y Jin, WJ Shin, W Park, S Chae… - …, 2021 - iopscience.iop.org
Traumatic brain injury is one of the leading causes of accidental death and disability. The
loss of parts in a severely injured brain induces edema, neuronal apoptosis, and …

BDNF, brain, and regeneration: insights from zebrafish

C Lucini, L D'Angelo, P Cacialli, A Palladino… - International journal of …, 2018 - mdpi.com
Zebrafish (Danio rerio) is a teleost fish widely accepted as a model organism for
neuroscientific studies. The adults show common basic vertebrate brain structures, together …

Neural stem cells promote neuroplasticity: a promising therapeutic strategy for the treatment of Alzheimer's disease

J Chang, Y Li, X Shan, X Chen, X Yan… - Neural Regeneration …, 2024 - journals.lww.com
Recent studies have demonstrated that neuroplasticity, such as synaptic plasticity and
neurogenesis, exists throughout the normal lifespan but declines with age and is …

Traumatic brain injury and stem cells: an overview of clinical trials, the current treatments and future therapeutic approaches

G Schepici, S Silvestro, P Bramanti, E Mazzon - Medicina, 2020 - mdpi.com
Traumatic brain injury represents physical damage to the brain tissue that induces transitory
or permanent neurological disabilities. The traumatic injury activates an important …

The roles of neurotrophins in traumatic brain injury

PH Lin, LT Kuo, HT Luh - Life, 2021 - mdpi.com
Neurotrophins are a collection of structurally and functionally related proteins. They play
important roles in many aspects of neural development, survival, and plasticity. Traumatic …

Cell-based therapies for traumatic brain injury: therapeutic treatments and clinical trials

C Bonilla, M Zurita - Biomedicines, 2021 - mdpi.com
Traumatic brain injury (TBI) represents physical damage to the brain tissue that induces
transitory or permanent neurological disabilities. TBI contributes to 50% of all trauma deaths …

Exosomes and nano-SDF scaffold as a cell-free-based treatment strategy improve traumatic brain injury mechanisms by decreasing oxidative stress …

M Hajinejad, MH Ebrahimzadeh… - Stem Cell Reviews and …, 2023 - Springer
Traumatic brain injury (TBI) causes a variety of complex pathological changes in brain
parenchymal tissue by increasing neuroinflammatory and apoptosis responses. Currently …

Extracellular vesicles mediate neuroprotection and functional recovery after traumatic brain injury

MK Sun, AP Passaro, CF Latchoumane… - Journal of …, 2020 - liebertpub.com
The lack of effective therapies for moderate-to-severe traumatic brain injuries (TBIs) leaves
patients with lifelong disabilities. Neural stem cells (NSCs) have demonstrated great …