Objectives There is significant interest in uncovering the mechanisms through which
exercise enhances cognition, memory, and mood, and lowers the risk of neurodegenerative …

Pain is an unpleasant sensory and emotional experience associated with, or resembling that
associated with, actual or potential tissue damage. The processing of pain involves …

Neuropathic pain is a chronic pain caused by central and peripheral nerve injury, long-term
diabetes or treatment with chemotherapy drugs, and it is dissimilar to other chronic pain …

Objective To explore whether MRI‐visible enlarged perivascular spaces (EPVS) are
associated with migraine and may serve as a predictor of migraine. Then further explore its …

Objective Evaluate the efficacy and tolerability of prazosin for prophylaxis of headaches
following mild traumatic brain injury in active‐duty service members and military veterans …

Vulnerability to chronic pain is found to depend on age and sex. Most patients with chronic
pain are elderly women, especially with posttraumatic pain after bone fracture that prevails …

Neuropathic pain (NP) remains an untreatable disease due to the complex pathophysiology
that involves the whole pain neuraxis including the forebrain. Sensory dysfunctions such as …

The reticular activating system (RAS) is a component of the reticular formation in vertebrate
brains located throughout the brainstem. Between the brainstem and the cortex, multiple …

Paclitaxel (sold under the brand name Taxol) is a chemotherapeutic drug that is widely used
to treat cancer. However, it can also induce peripheral neuropathy, which limits its use …

The glymphatic system is network of perivascular spaces through which cerebrospinal fluid
and interstitial fluid can move through the brain, clearing metabolic waste, such as amyloid …