Vascularization is fundamental to the growth and spread of tumor cells to distant sites. As a
consequence, angiogenesis, the sprouting of new blood vessels from existing ones, is a …

The tumor microenvironment (TME) is a complex system composed of multiple cells, such as
non-cancerous fibroblasts, adipocytes, immune and vascular cells, as well as signal …

Fisetin (FS) is an anticancer drug having potential role in oral tumors management.
However, its clinical application is limited due to its hydrophobicity and instability. Bioactive …

Vascular mimicry is induced by a wide array of genes with functions related to cancer
stemness, hypoxia, angiogenesis and autophagy. Vascular mimicry competent (VM …

Tumor microenvironment (TME) is characterized by mutual interactions of the tumor, stromal
and immune cells. Early and advanced colorectal tumors differ in structure and present …

Thiosemicarbazones are known for their biological and pharmacological activities. In this
study, we have synthesized and characterized 3-Methoxybenzaldehyde thiosemicarbazone …

Aggressive pituitary tumors (APTs) are associated with significant morbidity and mortality,
and effective treatment options are limited. Immune checkpoint inhibitors (ICIs) have …

Our understanding of angiogenesis has significantly expanded over the past five decades.
More recently, research has focused on this process at a more molecular level, looking at it …

Cancer stem cells (CSCs) are self-renewing multipotent cells that play a vital role in the
development of cancer drug resistance conditions. Various therapies like conventional …

At present, drug delivery strategies for minimizing unwanted toxicity to healthy cells and
improving the therapeutic efficacy have gained greater momentum, especially for lung …