A cell-free DNA metagenomic sequencing assay that integrates the host injury response to infection

AP Cheng, P Burnham, JR Lee… - Proceedings of the …, 2019 - National Acad Sciences
High-throughput metagenomic sequencing offers an unbiased approach to identify
pathogens in clinical samples. Conventional metagenomic sequencing, however, does not …

[HTML][HTML] Point-of-Care Autofluorescence Imaging for Real-Time Sampling and Treatment Guidance of Bioburden in Chronic Wounds: First-in-Human Results

RS DaCosta, I Kulbatski, L Lindvere-Teene, D Starr… - Plos one, 2015 - journals.plos.org
Background Traditionally, chronic wound infection is diagnosed by visual inspection under
white light and microbiological sampling, which are subjective and suboptimal, respectively …

[HTML][HTML] Evaluation of Malondialdehyde Levels, Oxidative Stress and Host–Bacteria Interactions: Escherichia coli and Salmonella Derby

V Tsaturyan, A Poghosyan, M Toczyłowski, A Pepoyan - Cells, 2022 - mdpi.com
Either extracts, cell-free suspensions or bacterial suspensions are used to study bacterial
lipid peroxidation processes. Along with gas chromatography-mass spectrometry, liquid …

Role of Dendritic Cells and Alveolar Macrophages in Regulating Early Host Defense against Pulmonary Infection with Cryptococcus neoformans

JJ Osterholzer, JE Milam, GH Chen… - Infection and …, 2009 - Am Soc Microbiol
Successful pulmonary clearance of the encapsulated yeast Cryptococcus neoformans
requires a T1 adaptive immune response. This response takes up to 3 weeks to fully …

A reappraisal of humoral immunity based on mechanisms of antibody‐mediated protection against intracellular pathogens

A Casadevall, L Pirofski - Advances in immunology, 2006 - Elsevier
Sometime in the mid to late twentieth century the study of antibody‐mediated immunity (AMI)
entered the doldrums, as many immunologists believed that the function of AMI was well …

Invasive infection due to Penicillium species other than P. marneffei

G Lyratzopoulos, M Ellis, R Nerringer, DW Denning - Journal of Infection, 2002 - Elsevier
Infection caused by Penicillium spp. due to species other than P. marneffei is rare. We
present three such cases of invasive disease. The first had chronic granulomatous disorder …

What is a host? Attributes of individual susceptibility

A Casadevall, L Pirofski - Infection and immunity, 2018 - Am Soc Microbiol
In every epidemic some individuals become sick and some may die, whereas others recover
from illness and still others show no signs or symptoms of disease. These differences …

PERISCOPE: road towards effective control of pertussis

DA Diavatopoulos, KHG Mills, KE Kester… - The Lancet Infectious …, 2019 - thelancet.com
The resurgence and changing epidemiology of pertussis in high-income countries, the high
infant mortality caused by pertussis in low-income countries, and the increasing morbidity in …

Peripatetic health-care workers as potential superspreaders

L Temime, L Opatowski, Y Pannet… - Proceedings of the …, 2009 - National Acad Sciences
Many nosocomial outbreaks exhibit “superspreading events” in which cross-transmission
occurs via a single individual to a large number of patients. We investigated how …

Fungal infections and the fungal microbiome in hepatobiliary disorders

P Hartmann, B Schnabl - Journal of hepatology, 2023 - Elsevier
Liver and biliary diseases affect more than a billion people worldwide, with high associated
morbidity and mortality. The impact of the intestinal bacterial microbiome on liver diseases …